Cefepime exposure in prolonged or intermittent infusion in critically ill children
Aims Cefepime is commonly used in critically ill children for whom there is a high between‐subject variability. To reach the therapeutic pharmacokinetic (PK) target in critically ill patients, prolonged infusion of beta‐lactams seems to be the most efficient.
Marc Hobeika +12 more
wiley +1 more source
Factors associated with health-related quality of life in patients with chronic liver disease in Korea: a cross-sectional study. [PDF]
Jung GM, Pahn J.
europepmc +1 more source
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley +1 more source
Exercise rehabilitation adherence and associated factors in patients aged ≥75 years with hemorrhagic stroke: a mixed-methods study. [PDF]
Wang Y, Lu L, Wei W.
europepmc +1 more source
When meta‐analyses mislead: Promises and pitfalls in teratology counselling
Meta‐analysis has become a central tool for evidence synthesis in clinical teratology, offering the promise of increased statistical power, earlier signal detection and consolidated guidance for teratology counselling. When conducted rigorously and interpreted carefully, pooled analyses can provide clinicians with a structured basis for risk ...
Yusuf Cem Kaplan, Nusret Uysal
wiley +1 more source
Economic evaluations of antiobesity medications: A systematic literature review
The global prevalence of obesity is rising rapidly. With several antiobesity medications approved and many more in development, understanding their economic value is increasingly important. This study reviews full economic evaluations of approved antiobesity medications to assess cost‐effectiveness and inform reimbursement and access decisions.
Martina Jurković +5 more
wiley +1 more source
Living in a genetic penumbra: navigating uncertainty and morality. [PDF]
Henry J, Sankar P, Sahota PKC.
europepmc +1 more source
A British Pharmacological Society Position Statement on Medications in Pregnancy and Lactation
British Journal of Clinical Pharmacology, EarlyView.
Agnesa Mustafa +14 more
wiley +1 more source
Adaptation of Parental Perception of Uncertainty Scale (PPUS): A psychometric study in a genetic research center in Indonesia. [PDF]
Larasati IA +4 more
europepmc +1 more source
Navigating Uncertainty in Pediatric Chronic Illness Care: A Hermeneutic Phenomenological Study of Nurses in Saudi Arabia. [PDF]
Alodhailah AM +5 more
europepmc +1 more source

