Results 91 to 100 of about 1,121,216 (274)

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Uncertainty Modeling of a Modified SEIR Epidemic Model for COVID-19. [PDF]

Biology (Basel), 2022
Wang Y, Wang P, Zhang S, Pan H.
europepmc   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Advances in Virtual Power Plant Operations: A Review of Optimization Models

IEEE Access
In recent decades, the global shift toward sustainable energy solutions has accelerated, prompting nations to integrate renewable energy sources (RES) into their electricity grids and adhere to international environmental protocols.
Fatemeh Marzbani, Ahmed H. Osman, Mohamed S. Hassan   +2 more
doaj   +1 more source

Assessment of Artificial Intelligence-Driven Fitness and Health Management Programs for Adolescents Using the SuperHyperSoft Set Framework [PDF]

Neutrosophic Sets and Systems
The rising use of artificial intelligence in adolescent fitness and health applications has created a need for more sophisticated evaluation frameworks.
Di Wu, Ali Khatibi, Jacquline Tham
doaj   +1 more source

A new 2D-3D registration gold-standard dataset for the hip joint based on uncertainty modeling. [PDF]

Med Phys, 2021
D'Isidoro F, Chênes C, Ferguson SJ, Schmid J.   +3 more
europepmc   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Averaging of Linear Quadratic Parabolic Optimal Control Problem

Axioms
This paper studies an averaged Linear Quadratic Regulator (LQR) problem for a parabolic partial differential equation (PDE), where the system dynamics are affected by uncertain parameters.
Olena Kapustian, Oleksandr Laptiev, Adalbert Makarovych   +2 more
doaj   +1 more source

A Neutrosophic TwoFold Algebra-Based Framework for Evaluating Practical Teaching Quality in Fashion Design and Technology Education [PDF]

Neutrosophic Sets and Systems
Assessing the quality of practical teaching in fashion design and technology programs is complex due to the subjective and multidimensional nature of creative education.
Guiling Ba
doaj   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source