Results 61 to 70 of about 1,213,467 (327)

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive care.
Amin Mehrabian, Peter Auguste, Amy Grove, Anna Brown, Janette Parr, Mubarak Patel, Furqan Butt, Jeremiah Donoghue, Mehdi Yousefi, Jo Parsons   +9 more
wiley   +1 more source

Black hole thermodynamics with generalized uncertainty principle

, 2009
In the standard viewpoint, the temperature of a stationary black hole is proportional to its surface gravity, $T_H=\hbar\kappa/2\pi$. This is a semiclassical result and the quantum gravity effects are not taken into consideration.
A. Ashtekar, B. Chen, C. Bambi, C. Bambi, C.B. Liang, D.N. Page, F. Scardigli, F. Scardigli, G. Amelino-Camelia, G. Veneziano, H.C. Ohanian, J. Preskill, K. Nouicer, Li Xiang, P.C. Vaidya, P.S. Custodio, R. Aloisio, R. Banerjee, R. Bousso, S. Carlip, S. Mukherji, T. Yoneya, W. Kim, X.Q Wen, Y. Ko, Z. Zheng   +25 more
core   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Generalized Uncertainty Principle from Quantum Geometry [PDF]

, 1999
The generalized uncertainty principle of string theory is derived in the framework of Quantum Geometry by taking into account the existence of an upper limit on the acceleration of massive particles.Comment: 9 pages, LATEX file, to appear in Int.
Capozziello, S., Lambiase, G., Scarpetta, G.   +2 more
core   +1 more source

The Conditional Uncertainty Principle

, 2018
We develop a general operational framework that formalizes the concept of conditional uncertainty in a measure-independent fashion. Our formalism is built upon a mathematical relation which we call conditional majorization.
Gour, Gilad, Grudka, Andrzej, Horodecki, Michał, Kłobus, Waldemar, Narasimhachar, Varun, Łodyga, Justyna   +5 more
core   +1 more source

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

Uncertainty Principles for Wigner-Ville Distribution Associated with the Linear Canonical Transforms

Abstract and Applied Analysis, 2014
The Heisenberg uncertainty principle of harmonic analysis plays an important role in modern applied mathematical applications, signal processing and physics community. The generalizations and extensions of the classical uncertainty principle to the novel
Yong-Gang Li, Bing-Zhao Li, Hua-Fei Sun
doaj   +1 more source

Quantum Mechanics from the Energy Circulation Theory — Wave Function Showing an Energy Location in the 3D Real Space

Reports in Advances of Physical Sciences, 2021
The Schrödinger equation is one of the cores in quantum mechanics, but bears a contradiction. In the process to obtain the energy and momentum operators, the relation [Formula: see text] is used for [Formula: see text].
Shigeto Nagao
doaj   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source