Results 71 to 80 of about 1,218,489 (324)

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Expanding Uncertainty Principle to Certainty-Uncertainty Principles with Neutrosophy and Quad-stage Method [PDF]

Neutrosophic Sets and Systems, 2015
The most famous contribution of Heisenberg is uncertainty principle. But the original uncertainty principle is improper. Considering all the possible situations (including the case that people can create laws) and applying Neutrosophy and Quad-stage ...
Fu Yuhua
doaj  

Generalized uncertainty principle: from the harmonic oscillator to a QFT toy model

European Physical Journal C: Particles and Fields, 2021
Several models of quantum gravity predict the emergence of a minimal length at Planck scale. This is commonly taken into consideration by modifying the Heisenberg uncertainty principle into the generalized uncertainty principle.
Pasquale Bosso, Giuseppe Gaetano Luciano
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Noncommutative Schwarzschild geometry and generalized uncertainty principle

European Physical Journal C: Particles and Fields, 2019
We discuss a possible link between the deformation parameter $$\Theta ^{\mu \nu }$$ Θμν arising in the framework of noncommutative geometry and the parameter $$\beta $$ β of the generalized uncertainty principle (GUP). We compute the shift of the Hawking
T. Kanazawa, G. Lambiase, G. Vilasi, A. Yoshioka   +3 more
doaj   +1 more source

The choice uncertainty principle [PDF]

Communications of the ACM, 2007
It is impossible to make an unambiguous choice between near-simultaneous events under a deadline. How can computations choose reliably?
openaire   +2 more sources

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

Natural extension of the Generalised Uncertainty Principle

, 2008
We discuss a gedanken experiment for the simultaneous measurement of the position and momentum of a particle in de Sitter spacetime. We propose an extension of the so-called generalized uncertainty principle (GUP) which implies the existence of a minimum
C Bambi, F R Urban, Perlmutter S, Riess A G, Scardigli F, Spergel D N, Stephani H   +6 more
core   +1 more source

Erythropoietin, uncertainty principle and cancer related anaemia

BMC Cancer, 2002
Background This study was designed to evaluate if erythropoietin (EPO) is effective in the treatment of cancer related anemia, and if its effect remains unchanged when data are analyzed according to various clinical and methodological characteristics of ...
Bennett Charles L, Adams Jared R, Clark Otavio, Djulbegovic Benjamin   +3 more
doaj   +1 more source