Results 251 to 260 of about 111,305 (313)

SAAP‐148 Oligomerizes into a Hexamer Forming a Hydrophobic Inner Core

ChemBioChem, Volume 26, Issue 12, June 16, 2025.
The highly cationic and hydrophobic antimicrobial peptide SAP‐148 effectively eradicates multidrug‐resistant bacteria, persistent cells, and biofilms without inducing resistance. Its efficiency is likely due to its ability to disrupt bacterial membranes as an oligomer, forming a stable alpha‐helical hexameric bundle with three parallel dimers that ...
Aden Hodzic, Djenana Vejzovic, Altea Topciu, Kirill Kuhlmann, Raj Kumar, Maria Andrea Mroginski, Alejandra de Miguel, Pia Hofmann, Klaus Zangger, Markus Weingarth, Robert A. Cordfunke, Jan W. Drijfhout, Peter Nibbering, Michal Belicka, Karl Lohner, Nermina Malanovic   +15 more
wiley   +1 more source

Observational constraints on the strength and depth of the zonal jets on Saturn. [PDF]

Nat Commun
Galanti E, Durante D, Iess L, Kaspi Y.
europepmc   +1 more source

LazyAct: Lazy actor with dynamic state skip based on constrained MDP. [PDF]

PLoS One
Zhang H, Chen Z, Deng H, Feng C.
europepmc   +1 more source

Wearable Electrohydraulic Actuation For Salient Full‐Fingertip Haptic Feedback

Advanced Materials Technologies, Volume 10, Issue 12, June 18, 2025.
This study introduces a wearable soft robotic system that combines a flat and conformable electrohydraulic pump, a mechanically transparent channel, and an ultra‐thin fingertip chamber to provide salient haptic feedback that imitates natural touch experiences.
Yitian Shao, Alona Shagan Shomron, Bernard Javot, Christoph Keplinger, Katherine J. Kuchenbecker   +4 more
wiley   +1 more source

Domain-Separated Quantum Neural Network for Truss Structural Analysis with Mechanics-Informed Constraints. [PDF]

Biomimetics (Basel)
Ha H, Shon S, Lee S.
europepmc   +1 more source

S‐ketamine Alleviates Neuroinflammation and Attenuates Lipopolysaccharide‐Induced Depression Via Targeting SIRT2

Advanced Science, Volume 12, Issue 23, June 20, 2025.
S‐ketamine binds directly to SIRT2, facilitating its interaction with NF‐κB p65. This interaction reduces the acetylation of NF‐κB p65 and inhibits its activation, thereby exerting anti‐inflammatory and antidepressant effects. Created by BioRender.
Cong Lin, Xiaoxuan Zhou, Mingqi Li, Cong Zhang, Haojiang Zhai, Haohong Li, Hongshuang Wang, Xiaohui Wang   +7 more
wiley   +1 more source

Accelerated optimization in deep learning with a proportional-integral-derivative controller. [PDF]

Nat Commun
Chen S, Liu J, Wang P, Xu C, Cai S, Chu J.   +5 more
europepmc   +1 more source

A Novel Dual‐Network Approach for Real‐Time Liveweight Estimation in Precision Livestock Management

Advanced Science, Volume 12, Issue 22, June 12, 2025.
A novel dual‐network framework is proposed for real‐time, non‐contact liveweight estimation of pigs. By extracting contour information instead of segmented images, the method achieves high accuracy (R2 = 0.993) and an exceptional speed of 1131.6 FPS. This approach enhances automation in livestock farming, providing a scalable and efficient solution for
Ximing Dong, Caiming Zhang, Peiyuan Wang, Dexuan Chen, Gang Jun Tu, Shuhong Zhao, Tao Xiang   +6 more
wiley   +1 more source

DC algorithm for estimation of sparse Gaussian graphical models. [PDF]

PLoS One
Shiratori T, Takano Y.
europepmc   +1 more source

DiffMC‐Gen: A Dual Denoising Diffusion Model for Multi‐Conditional Molecular Generation

Advanced Science, Volume 12, Issue 22, June 12, 2025.
DiffMC‐Gen, a dual‐diffusion model for 2D and 3D molecular generation, simultaneously optimizes multiple key objectives across the drug design process, enabling the generation of novel, target‐specific small‐molecule ligands with high therapeutic potential.
Yuwei Yang, Shukai Gu, Bo Liu, Xiaoqing Gong, Ruiqiang Lu, Jiayue Qiu, Xiaojun Yao, Huanxiang Liu   +7 more
wiley   +1 more source