Results 221 to 230 of about 102,674 (250)

The NF-κB transcription factor RelA directs mucosal-associated invariant T-cell development. [PDF]

open access: yesImmunol Cell Biol
Fulford TS   +15 more
europepmc   +1 more source

Unconventional T cells and kidney disease [PDF]

open access: yesNature Reviews Nephrology, 2021
Unconventional T cells are a diverse and underappreciated group of relatively rare lymphocytes that are distinct from conventional CD4+ and CD8+ T cells, and that mainly recognize antigens in the absence of classical restriction through the major histocompatibility complex (MHC).
Hannah Kaminski   +2 more
exaly   +3 more sources

The duplexity of unconventional T cells in cancer [PDF]

open access: yesInternational Journal of Biochemistry and Cell Biology, 2022
Unconventional T cells and their involvement in cancer are understudied in comparison to conventional T cells, but recent findings indicate that these cells play important roles in both cancer progression and inhibition. Here, we briefly review the dichotomous role of three unconventional T cell lineages: γδ T cells, MAIT cells and NKT cells.
Robert Wiesheu, Seth B Coffelt
exaly   +3 more sources
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Swine unconventional T cells

Developmental & Comparative Immunology, 2022
Pigs are important domestic livestock and a comprehensive understanding of their immune system is critical to improve swine vaccine efficacy. Pig models represent an excellent animal model for immunological studies because of their anatomical and physiological similarities to humans.
Miaomiao Wu   +4 more
openaire   +2 more sources

The burgeoning family of unconventional T cells

Nature Immunology, 2015
While most studies of T lymphocytes have focused on T cells reactive to complexes of peptide and major histocompatibility complex (MHC) proteins, many other types of T cells do not fit this paradigm. These include CD1-restricted T cells, MR1-restricted mucosal associated invariant T cells (MAIT cells), MHC class Ib-reactive T cells, and γδ T cells ...
Dale Godfrey   +2 more
exaly   +3 more sources

Thymic development of unconventional T cells: how NKT cells, MAIT cells and γδ T cells emerge

Nature Reviews Immunology, 2020
T cell lineages are defined by specialized functions and differential expression of surface antigens, cytokines and transcription factors. Conventional CD4+ and CD8+ T cells are the best studied of the T cell subsets, but 'unconventional' T cells have emerged as being more abundant and influential than has previously been appreciated.
Daniel G Pellicci   +2 more
exaly   +3 more sources

Unconventional T Cells

2010
1 Defining Unconventional T Cells 2 Subtypes of Unconventional T Cells: γδ T Cells 3 Subtypes of Unconventional T Cells: αβ T Cells Keywords: unconventional T cells; defining unconventional T cells; ‘professional’ antigen-presenting cells (APC); TCR gene cDNA (complementary DNA); murine dendritic epidermal T cells (DETC ...
Adrian Hayday, Carrie Steele
openaire   +1 more source

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