Results 1 to 10 of about 166 (77)

Efficacy and safety of native type II collagen in modulating knee osteoarthritis symptoms: a randomised, double‐blind, placebo‐controlled trial [PDF]

Journal of Experimental Orthopaedics, 2022
Purpose Knee osteoarthritis (OA) is the most common form of clinical arthritis in middle‐aged and older individuals. Undenatured or native type II (TII) collagen derived from the chicken sternum has a good therapeutic effect on relieving severe pain of ...
Cheng Luo, Weike Su, Ying Song, Shalini Srivastava   +3 more
doaj   +3 more sources

Undenatured type II collagen for knee osteoarthritis [PDF]

Annals of Medicine
Introduction: Knee Osteoarthritis (OA) leads to significant pain and reduced function and affects patients’ overall quality of life (QoL). Conservative modalities are the first line of management, resorting to surgery only if they fail.
Ashim Gupta, Nicola Maffulli
doaj   +4 more sources

Efficacy and tolerability of native (undenatured) type II collagen supplementation for joint health in healthy volunteers: a randomized double-blind placebo-controlled study [PDF]

Nutrition Journal
Background In non-osteoarthritic individuals, the appearance of joint discomfort with physical activity is a potential indicator of initial joint degeneration. The present study aimed to evaluate the efficacy and tolerability of native (undenatured) type-
Ingrid Möller, Kirsten Martínez, Andrea Terradillos-Guillén, Ester Costa-Larrión, Daniel Martínez-Puig, Javier Velasco-Álvarez   +5 more
doaj   +2 more sources

Tissue adhesives for wound closure. [PDF]

Smart Med, 2023
In this paper, we present an up‐to‐date review of tissue adhesives for wound closure. We mainly discussed the fundamental design requirements for the adhesives, the fabrication of tissue adhesives, and the application of tissue adhesives on skin healing, corneal patch, and gastrointestinal tissues.
Kong B, Qi C, Wang H, Kong T, Liu Z.
europepmc   +2 more sources

On the prospects for the use of undenatured type II collagen in the treatment of osteoarthritis and other joint diseases

Современная ревматология, 2022
Standardized extracts of undenatured type II collagen (UC-II) are used as alternative approaches to the treatment of osteoarthritis (OA). The effect of UC-II extracts is associated with the modulation of the mechanisms of innate and acquired immunity, a ...
O. A. Gromova, I. Yu. Torshin, A. M. Lila, O. A. Shavlovskaya   +3 more
doaj   +1 more source

Resolution of the Council of Experts “Results of a multicenter, randomized, double-blind, placebo-controlled study of ARTNEO in patients with stage II–III primary knee osteoarthritis”

Современная ревматология, 2023
On August 31,2023 in V.A. Nasonova Research Institute of Rheumatology a meeting of the Expert Council was held at which the principal investigators and co-investigators of the ARTNEO-2021 protocol "Multicenter randomized double-blind, placebo-controlled ...
A. M. Lila, L. I. Alekseeva, I. B. Belyaeva, I. B. Vinogradova, N. A. Demidova, O. V. Kalyuzhin, I. I. Nesterovich, V. N. Sorotskaya, L. Yu. Shirokova, S. P. Yakupova   +9 more
doaj   +1 more source

The value of undenatured collagen for the normalization of the function of the cartilaginous tissue of the joints

Медицинский совет, 2022
Among the proteins of the human body, collagen accounts for at least 25–45% collagen; it is an essential structural component of skeletal tissues, connective tissue of internal organs (heart, intestines, lungs, liver, kidneys), as well as blood vessels ...
I. S. Dydykina, P. S. Kovalenko, A. A. Kovalenko, A. V. Aboleshina   +3 more
doaj   +1 more source

Protein‐based Nanoparticles: From Drug Delivery to Imaging, Nanocatalysis and Protein Therapy

Angewandte Chemie International Edition, Volume 62, Issue 44, October 26, 2023., 2023
In the last decade, significant progress was made in the development of protein nanoparticles, transitioning from artificial assemblies for drug delivery, to multifunctional systems for nanocatalysis and protein therapy. Advanced biohybrid materials, combined with dynamic chemistries and mild methods of particle formation produce nanoparticles that ...
Jonas Kaltbeitzel, Peter R. Wich
wiley   +1 more source

Preventative and therapeutic potential of animal milk components against COVID‐19: A comprehensive review

Food Science &Nutrition, Volume 11, Issue 6, Page 2547-2579, June 2023., 2023
Therapeutics properties of animal milk components against pathogenic viruses such as COVID‐19. Abstract The global pandemic of COVID‐19 is considered one of the most catastrophic events on earth. During the pandemic, food ingredients may play crucial roles in preventing infectious diseases and sustaining people's general health and well‐being.
Parminder Singh, Roberto Hernandez‐Rauda, Oscar Peña‐Rodas   +2 more
wiley   +1 more source

Preparation of Collagen Peptide Nanoliposomes From Sturgeon Fish Cartilage and Explore Their Anti‐Osteoarthritis Effects in Rats

Food Frontiers, Volume 6, Issue 2, Page 727-749, March 2025.
This study aims to extract pepsin soluble collagen from sturgeon cartilage, hydrolyze to collagen peptides and prepare SCCP nanoliposomes to explore the treatment effects of osteoarthritis in rats. ABSTRACT This study aims to extract pepsin soluble collagen (PSC) from sturgeon cartilage, hydrolyze to sturgeon cartilage collagen peptides (SCCP), and ...
Chia‐Chi Kung, Mei‐Zhen Lin, Bing‐Huei Chen   +2 more
wiley   +1 more source