Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs +7 more
wiley +1 more source
Life is Cheap: Using Mortality Bonds to Hedge Aggregate Mortality Risk [PDF]
Using the widely-cited Lee-Carter mortality model, we quantify aggregate mortality risk as the risk that the average annuitant lives longer than is predicted by the model, and we conclude that annuity business exposes insurance companies to substantial ...
Leora Friedberg, Anthony Webb
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ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes +75 more
wiley +1 more source
Evaluating global health programmes targeting under-5 mortality: problems and recommendations. [PDF]
Kenny A +9 more
europepmc +1 more source
Assessment of the quality of the vital registration system for under-5 mortality in Yucatan, Mexico. [PDF]
Hernandez B +10 more
europepmc +1 more source
Report of the International Conference on the Perinatal and Infant Mortality Problem of the United States [PDF]
Summary of the presentations and discussions at the International Conference on the Perinatal and Infant Mortality Problem of the United States, Washington, D.
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Human Pegivirus Encephalitis With Brain Detection and Response to Sofosbuvir Ledipasvir
ABSTRACT Human pegivirus (HPgV‐1) has been associated with severe encephalomyelitis in immunocompromised patients. Its neurological spectrum remains poorly defined. We report a slowly progressive encephalitis in a person living with well‐controlled HIV, characterized by white matter abnormalities and inflammatory cerebrospinal fluid (CSF). HPgV RNA was
Antoine Moulignier +3 more
wiley +1 more source
Under-5 mortality of infectious diseases in 204 countries between 1990 and 2021. [PDF]
Tan J +6 more
europepmc +1 more source
The Urban-Rural Gap in under-5 Mortality Rate Narrowed in China, 1991-2019. [PDF]
Chen L, Wang Z.
europepmc +1 more source
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie +8 more
wiley +1 more source

