Results 91 to 100 of about 988,592 (311)

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source

The economic burden of measles in children under five in Uganda

Vaccine: X, 2020
هناك أدلة محدودة للغاية حول التكلفة الاقتصادية للحصبة في البلدان منخفضة الدخل. لقد قدرنا تكلفة علاج الحصبة في أوغندا من منظور مجتمعي. أجرينا دراسة لتكلفة المرض على أساس الإصابة في أوغندا. أجرينا مسحًا على موظفي المنشأة، وسجلنا النفقات المتعلقة بالمستشفى لمرضى الحصبة. أجرينا مقابلات مع مقدمي الرعاية للأطفال المصابين بالحصبة في 48 منشأة رعاية صحية مختارة.
Gatien de Broucker, Anthony Ssebagereka, Rebecca Racheal Apolot, Aloysius Mutebi, Elizabeth Ekirapa–Kiracho, Bryan Patenaude, Dagna Constenla   +6 more
openaire   +3 more sources

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

How to prevent 804,000 children under five dying

, 2013
Exclusive breastfeeding infants until six months of age can prevent 804,000 under five deaths each year however less than 40% of infants worldwide are.
Keith, R.
core  

Malnutrition among children under the age of five in the Democratic Republic of Congo (DRC) : does geographic location matter? [PDF]

, 2011
Background: Although there are inequalities in child health and survival in the Democratic Republic of Congo (DRC), the influence of distal determinants such as geographic location on children’s nutritional status is still unclear.
Francesco P Cappuccio, Kandala Ngianga-Bakwin, Ngianga-Bakwin Kandala, Jacques BO Emina, Kandala, Ngianga-Bakwin, Emina Jacques BO, Madungu, Tumwaka P., Nzita Kikhela, D., Nzita Kikhela PD, Cappuccio, Francesco, Cappuccio Francesco P, Madungu Tumwaka P, Emina Be-Ofuriyua, Jacques, Tumwaka P Madungu, Kikhela PD Nzita   +14 more
core   +1 more source

Prevalence of Cryptosporidiosis in diarrhoeal stools of children under-five years seen in Ahmadu Bello University Teaching Hospital Zaria, Nigeria

Nigerian Journal of Paediatrics
Introduction: Human cryptosporidiosis is a zoonotic disease and is increasingly recognized as a major public health problem. It is associated with significant effects on growth, physical and cognitive functions and excess mortality especially among ...
Musa S, Yakubu AM, Olayinka AT
doaj  

Assessment of the Management of Diarrhoea Among Children Under Five in Addis Ababa, Ethiopia

Pediatric Health, Medicine and Therapeutics, 2020
Arega Gashaw Tsige,1 Teshome Nedi,2 Tigist Bacha3 1Department of Pharmacy, College of Health Sciences, Mekelle University, Mekelle, Ethiopia; 2Department of Pharmacology and Clinical Pharmacy, College of Health Sciences, Addis Ababa University, Addis ...
Tsige AG, Nedi T, Bacha T
doaj  

Prominent Movement Disorders in RNU2‐2‐Related Spliceosomopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Pediatric movement disorders often overlap with neurodevelopmental diseases, suggesting shared molecular mechanisms. Variants in small nuclear RNA (snRNA) genes encoding spliceosome components have recently been associated with neurodevelopmental disorders, termed “RNUopathies.” We analyzed genome sequencing data from 14 patients with ...
Magdalena Krygier, Ugo Sorrentino, Matias Wagner, Marta Zawadzka, Anna Lemska, Maria Mazurkiewicz‐Bełdzińska, Michael Zech   +6 more
wiley   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Knowledge and perception regarding pneumonia in children under five among parents at paediatric clinic in government hospital, Selangor (2021)

, 2021
Background of study:In Malaysia, pneumonia had contributed to 6% of child death in 2010. Parents’ who have poor knowledge and perception toward childhood pneumonia will have a tendency to delay treatment seeking behaviour.
Ong, Swee Leong, Japar, Salimah, Soh, Kim Lam, Soh, Kim Geok, Enoi, Sunnari, Abdul Raman, Rosna   +5 more
core