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Current genome‐reduction methods work in a trial‐and‐error fashion, constituting a long‐standing bottleneck in the research. We developed CREAT (CRISPR‐based genome trimming with a multi‐homology‐arm template), a CRISPR‐based genetic approach that enables systematically classifying essential versus non‐essential genomic regions and subsequently ...
Guanhua Yuan +7 more
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Improving forest aboveground carbon storage estimation by fusing spaceborne LiDAR features and three-dimensional enhanced spectral indices. [PDF]
Long Y, Sun H, Wang B, Jiang F.
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Underestimated barrier effects of ocean fronts shape global fishery distribution. [PDF]
Xing Q +7 more
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Application of Dang Van Model Based on Critical Plane Approach for Rolling Contact Problems. [PDF]
Romanowicz PJ.
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An Underestimation Bias in the Numerical Perception of Rewarding Stimuli: An ERP Study. [PDF]
Xue X, Yao Y.
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Reframing Mechanistic and Clinical Paradigms of Osimertinib-Associated Cardiotoxicity. [PDF]
Zhao D, Li D.
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Agreement between seroprevalence- and model-based estimates of COVID-19 burden. [PDF]
Owusu-Boaitey N +6 more
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The underestimated impact of cachexia
Expert Opinion on Drug Discovery, 2009This editorial contains views on the importance of animal research in the field of cachexia, a crippling syndrome associated with almost all chronic diseases that dramatically impact on quality of life and survival of the patient. Unfortunately, it is infrequently identified or diagnosed and too rarely treated.
Springer, Jochen, Anker, Stefan D.
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