Results 141 to 150 of about 2,738,424 (374)
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
WSCDL to WSBPEL: A Case Study of ATL-based Transformation [PDF]
, 2011 The ATLAS Transformation Language (ATL) is a hybrid transformation language that combines declarative and imperative programming elements and provides means to define model transformations. Most transformations using ATL reported in the literature show a
Ferreira Pires, Luis +4 more
core +1 more source
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Linking Theory and Practice: Performing a Reality Check on a Model of IS Success [PDF]
, 2005 The issue of ‘rigour vs. relevance’ in IS research has generated an intense, heated debate for over a decade. It is possible to identify, however, only a limited number of contributions on how to increase the relevance of IS research without compromising
Rosemann, Michael, Vessey, Iris
core +3 more sources
Understanding Understanding and Non-Understanding: The Problems and Possibilities
, 2021 Life is not limited to the coordinated functioning of millions of cells that make an individual or to one’s struggle for survival. It’s also about our pursuit to reach the Ultimate, or the Absolute in Hegel’s terms. In his search for the absolute, he too yearned for someone who would truly understand him.
openaire +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The Connection between Customer Satisfaction and Loyalty in the Field of Commercial Banks.Part 1 [PDF]
In this study, I address the following questions that are becoming increasingly important to bank managers: How are the levels of customer satisfaction and loyality when chosen online service?
Attila Bátor, György Kadocsa
core
CCT4 promotes tunneling nanotube formation
FEBS Letters, EarlyView.Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto +3 more
wiley +1 more source
Transforming Informed Consent Generation Using Large Language Models: Mixed Methods Study
JMIR Medical InformaticsBackgroundInformed consent forms (ICFs) for clinical trials have become increasingly complex, often hindering participant comprehension and engagement due to legal jargon and lengthy content. The recent advances in large language models (LLMs) present an
Qiming Shi +8 more
doaj +1 more source