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Nietzsche e o projeto crítico de superação da compreensibilidade

open access: yesCadernos Nietzsche
O objetivo do texto é analisar o que denominamos projeto crítico de superação da compreensibilidade, a partir de três hipóteses: a) a temporalização do pensamento, remontando-o às condições individuais do emprego de um conceito, um signo, uma ação, etc.;
Jorge Luiz Viesenteiner
doaj  

Understanding Kantian Understanding [PDF]

open access: yes, 2018
Over the last decade or so philosophers have become increasingly dissatisfied with the dominant focus on the notion of knowledge in contemporary epistemology. Understanding, it has been suggested, is an important intellectual goal, often valuable over and above knowing the facts.
openaire   +2 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

FINANCIAL REPORTING IN THE LODGING INDUSTRY FROM THE SEGMENT REPORTING ASPECT [PDF]

open access: yes
Quality of accounting reporting system reflects the accomplisheddevelopment stage of the accounting information system and its ability to satisfydifferent external and internal accounting information needs. One of the mostimportant sources of information
Andor Pajrok
core  

Using an extended Technology Acceptance Model to understand students’ use of e-learning during Covid-19: Indonesian sport science education context

open access: gold, 2020
Sukendro Sukendro   +6 more
openalex   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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