Results 241 to 250 of about 2,791,166 (373)

Exploring the Understandability of a Hybrid Process Design Artifact Based on DCR Graphs

BPMDS/EMMSAD@CAiSE, 2019
Amine Abbad Andaloussi, Andrea Burattin, Tijs Slaats, Anette C. M. Petersen, Thomas T. Hildebrandt, B. Weber   +5 more
semanticscholar   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Comparative Evaluation of Artificial Intelligence Chatbots in Delivering Palliative Care Education to Intensive Care Unit Caregivers- A Cross-platform Analysis: A Brief Communication. [PDF]

Indian J Crit Care Med
Singh R, Gondode PG, Duggal S, Nayak SS.
europepmc   +1 more source

Hybrid Hydrogels for Tissue Mimics: Multimodal native imaging to understand structure and cell interactions

Bezirtzoglou, Ioanna, Norman, Chelsea, Zhu, Xinyi, Dumoux, Maud, Poologasundarampillai, Gowsihan, Darrow, Michele C   +5 more
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Enhancing patient participation in emergency department through patient-friendly clinical notes generated by large language models. [PDF]

Sci Rep
Kim SI, Park J, Kim T, Seo W, Kim T, Cha WC, Hong H.   +6 more
europepmc   +1 more source

Applying Sen's Capability Approach to Understand Work and Income among Poor People in India

, 2015
Mahasweta M. Banerjee
openalex   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Large Language Models vs. Professional Resources for Post-Treatment Quality-of-Life Questions in Head and Neck Cancer: A Cross-Sectional Comparison. [PDF]

Curr Oncol
Alabdalhussein A, Al-Khafaji MH, Nadeem S, Basharat M, Aldallal H, Mohammed MES, Alghnaimawi S, Al Yousif A, Baban J, Hamad S, Saleem I, Mozan S, Mair M.   +12 more
europepmc   +1 more source