Results 301 to 310 of about 2,791,166 (373)

Quality and Reliability of Adolescent Sexuality Education on Chinese Video Platforms: Sentiment-Topic Analysis and Cross-Sectional Study. [PDF]

JMIR Form Res
Wang L, Shu X, Huang J, Yan W, Zhao D.
europepmc   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Evaluating the Quality of Cardiovascular Disease Information From AI Chatbots: A Comparative Study. [PDF]

Cureus
Singavarapu J, Khemlani A, Jacobs M, Berglas E, Lazar J, Kabarriti A.   +5 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Smartphone Application-Based Rehabilitation Program for Older Adults With Type 2 Diabetes Mellitus: Insights From the Design, Development, and Validation. [PDF]

J Diabetes Sci Technol
Agnes T, Maiya GA, Kulakarni MM, Hegde SR, Ballal K, Balachandra M.   +5 more
europepmc   +1 more source

Understanding understanding

, 2015
openaire   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Comprehensibility and readability of selected artificial intelligence chatbots in providing uveitis-related information. [PDF]

Medicine (Baltimore)
Sönmezoğlu Hİ, Sönmezoğlu Hİ, Güner Sönmezoğlu B, Temel MH, Çakir B.   +4 more
europepmc   +1 more source

Quality and Dissemination of Uterine Fibroid Health Information on TikTok and Bilibili: Cross-Sectional Study. [PDF]

JMIR Form Res
Wang L, Chen Y, Zhao D, Xu T, Hua F.
europepmc   +1 more source