Results 51 to 60 of about 1,322 (215)

Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration

Advanced Science, EarlyView.
This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya, Huizhan Liu, Sarath Vijayakumar, Celia Bloom, Zhenhang Xu, Shu Tu, Benjamin J. Borgmeier, Mi Zhou, Litao Tao, Bechara Kachar, David Z. He   +10 more
wiley   +1 more source

Study on Damage Behavior and Anti-Explosion Performance of Steel Fiber-Reinforced Cellular Concrete Under Underwater Contact Explosion

Buildings
To explore the damage mitigation mechanism of steel fiber-reinforced cellular concrete (SFR-CC) under underwater explosion loading, this study systematically analyzes two key variables: steel fiber volume fraction (0.5%, 1.0%, 1.5%, and 2.0%) and ...
Hu Huang, Shubo Dai, Kelei Cao, Changxing Tang, Xiancai Zhang, Changhui Zhang, Qingming Qiu   +6 more
doaj   +1 more source

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source

Numerical Simulation Accuracy Study of Underwater Explosion Shock Waves

水下无人系统学报
In the numerical simulation study of the underwater explosion, the grid size and the artificial viscosity coefficient of the primary term have a large impact on the calculation results of the peak pressure of the shock wave.
Qiyuan AO, Xi LU, Zhiya JIANG, Poge KANG
doaj   +1 more source

Leading the Pack: Next‐Generation Batteries for Humanoid Robotics

Advanced Science, EarlyView.
Humanoid robots challenge traditional and anticipated energy technologies. Humanoid robot benchmarks of runtimes and energy demands for industry applications inform humanoid robot battery design choices at the cell level, pack level, and system level.
Matthew Bergschneider, Jiaqi Ke, Jin Luo, Laisuo Su, Thomas Campbell, Yue Zhou, Kyeongjae Cho   +6 more
wiley   +1 more source

Nanovesicles With Mechanically Induced Adjuvanticity for Robust Melanoma Vaccination Toward Tumor‐Associated Macrophages

Advanced Science, EarlyView.
Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley   +1 more source

The Requirement for Hydrostatic Initialisation in LS-DYNA/USA Finite Element Models

Shock and Vibration, 2000
The LS-DYNA/USA (Underwater Shock Analysis) coupled finite element codes are being investigated as a tool for predicting the local response of compliant plate structures subjected to far-field underwater explosion.
Lloyd Hammond, Raphael Grzebieta
doaj   +1 more source

Chemical‐Biological Fixation for Enhanced Bone Augmentation in Guided Bone Regeneration

Advanced Science, EarlyView.
M2N2ACa is an innovative injectable thermoresponsive barrier membrane adhesive to achieve reliable bone graft fixation. It provides strong wet adhesion and promotes the bio‐stabilization mediated by coagulation through controlled calcium release. This dual‐fixation strategy combines external chemical fixation and internal biological fixation via clot ...
Yu‐zhu Wang, Gao‐peng Dang, Zhi‐ting Li, Zhi‐hong Feng, Que Bai, Jia‐xin Hao, Xiao‐qing Cao, Tao Ye, Jing Li, Franklin R. Tay, Malcolm Xing, Ming Fang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

The Fluid-Solid Interaction Dynamics between Underwater Explosion Bubble and Corrugated Sandwich Plate

Shock and Vibration, 2016
Lightweight sandwich structures with highly porous 2D cores or 3D (three-dimensional) periodic cores can effectively withstand underwater explosion load.
Hao Wang, Yuan Sheng Cheng, Jun Liu, Lin Gan   +3 more
doaj   +1 more source

Smoothed particle hydrodynamics simulation of underwater explosions with dynamic particle refinement

AIP Advances, 2020
The underwater explosion is a very complex multiphase phenomenon that poses a threat to the safety of ocean structures. Numerical simulation is of great significance in understanding the underlying mechanisms of hydrodynamics and structural damages due ...
Tieshuan Zhuang, Xiangwei Dong
doaj   +1 more source