Results 71 to 80 of about 96,420 (244)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Testing strategies to enhance transplant success under stressful conditions at a tidal marsh restoration project

Restoration Ecology
Tidal marsh restoration is becoming an increasingly common tool to plan for future sea level rise. Subsided marshes' elevation can be restored through sediment additions, which may necessitate the reestablishment of vegetation.
Rachel Pausch
semanticscholar   +1 more source

Essais de revégétalisation par des espèces locales d'anciens sites miniers de la région de Thio [PDF]

, 1993
Ces essais avaient pour but de tester certaines espèces locales pour restaurer d'anciens terrains miniers et d'analyser leur adaptabilité, leurs modalités d'implantation et leur durabilité pour obtenir une couverture ...
Jaffré, Tanguy, Rigault, Frédéric, Sarrailh, J.M.   +2 more
core  

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Revegetated riparian areas are dominated by weeds, and lack structural diversity and natural recruitment: lessons for restoration practice

Restoration Ecology
Riparian areas can be highly biodiverse and provide critical ecosystem services. However, they are frequently subject to anthropogenic impacts such as land clearing, agricultural use, and urban development.
Eliza Foley‐Congdon, Sacha Jellinek, Y. E. Chee, J. Greet   +3 more
semanticscholar   +1 more source

Developing ecosystem service indicators: experiences and lessons learned from sub-global assessments and other initiatives [PDF]

, 2011
People depend upon ecosystems to supply a range of services necessary for their survival and well-being. Ecosystem service indicators are critical for knowing whether or not these essential services are being maintained and used in a sustainable manner ...
Armenteras, Dolors, Ash, Neville, Barano, Thomas, Beltrame, Coralie, Berg, Hakan, Bhagabati, Nirmal, Biala, Katarzyna, Birge, Traci, Bondarev, Alexander, Brown, Claire, Butchart, Stuart, Davidson, Nick, De Groot, Rudolf, Doswald, Natalie, Díaz, Sandra, Espaldon, Maria Victoria, Fuentes, Rodrigo, Garcia, Keisha, Ghate, Utkarsh, Girvan, Alexander, Goethals, Peter, Hadian, Oki, Höft, Robert, Koleff, Patricia, Kumar, Chetan, Larigauderie, Anne, Lasco, Rodel, Layke, Christian, Linstead, Conor, Luque Panadero, Victoria Eugenia, Mainka, Sue, Mapendembe, Abisha, Marcela, Mónica, Nybo, Signe, O'Farell, Patrick, Reyers, Belinda, Ricketts, Taylor, Ringold, Paul, Rodríguez Rodríguez, Davíd, Rosenthal, Amy, Sandlund, Odd Terje, Sarukhán, José, Scharlemann, Jorn, Schlatter, Christian, Simpson, Lucy, Stott, Andrew, Tierney, Megan, Tyrell, Tristan, UNEP-WCMC, -, Urquiza, Tania, Vackár, David, van Oudenhoven, Alexander, Viglizzo, Ernesto, Walpole, Matt, Watts, Jim, Williams, James, Yashina, Tatyana, Zandri, Edoardo   +57 more
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

La G.C.E.S. : une nouvelle stratégie de lutte anti-érosive appliquée à l'aménagement de terroirs en zone soudano-sahélienne du Burkina-Faso [PDF]

, 1992
Face à la dégradation de la végétation, des sols et du réseau hydrographique de la région soudano-sahélienne d'Afrique occidentale, et face à l'échec des méthodes d'équipement rural, les auteurs proposent une approche où la participation des intéressés ...
Dugué, P., Rodriguez, L., Roose, Eric
core  

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source