Results 131 to 140 of about 4,602 (244)

Geospatial Settlement Data and Immunization Reach in Polio SIAs: Evidence from Axis of Intractable Transmission States in Northern Nigeria. [PDF]

Gates Open Res
Shehu A, Metiboba L, Ohiaeri N, Ilesanmi O, Akpan D, Fashoto B, Nwakaogor GU, Fawaz A, Akhigbe O, Odukoya A, Akindipe O, Daniel F.   +11 more
europepmc   +1 more source

Numerical Simulation on Mechanical Response of Buried Pipeline under Uneven Settlement [PDF]

Proceedings of the 2017 2nd International Conference on Modelling, Simulation and Applied Mathematics (MSAM2017), 2017
Luzhen Jiang, Mei Yang, Dongdong Li, Qikun Ma, Yanhua Chen   +4 more
openaire   +1 more source

Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo

Advanced Science, EarlyView.
As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao, Zhijin Tian, Luqi Weng, Kun Xu, Dingyi Han, Zhaowei Wu, Junnan Li, Shangpu Li, Qijing Zhang, Xiaohui Zhao, Guoling Li, Yinghui Wei, Zhen Gu   +12 more
wiley   +1 more source

Abnormal mechanical load aggravates subchondral bone remodeling and uneven tibial plateau settlement in knee osteoarthritis via activation of osteoblast Piezo1-Ca²⁺-JAK2/STAT3 signaling. [PDF]

Int J Biol Sci
Li H, Zhang S, Feng C, Cheng F, Han Y, Wang M, Zhou S, Shao W, Chen W, Chen J, Liu K, Zhang Y, Wang J.   +12 more
europepmc   +1 more source

Artificial Intelligence‐Empowered Single‐Cell Phenotyping for Rapid, Automated Pathogen Diagnostics

Advanced Science, EarlyView.
This work presents an integrated diagnostic platform that combines microfluidic single‐cell bacterial detection with artificial intelligence‐driven analysis for rapid antimicrobial susceptibility testing. Single‐cell phenotyping enables assessment of antibiotic response in only a few cell replication cycles, while AI analysis supports precise bacterial
Sabita Khadka, Bushra Raahat, Spyros Tragoudas, Hui Li   +3 more
wiley   +1 more source

Aging, climate change, and the paradox of preparedness: Reflections from Villa El Salvador, Lima, Peru. [PDF]

PLOS Glob Public Health
Majidulla A, Flores-Flores O.
europepmc   +1 more source

Designing Tissue Function Through Embedded Bioprinting Architectures

Advanced Science, EarlyView.
Embedded bioprinting enables soft, cell‐dense constructs to be fabricated within supporting bath environments. This review introduces a function‐guided framework linking target tissue functions to architectural requirements, supporting bath selection, bioink design, printing dynamics, and validation assays.
Qi Li, Yifei Cao, Jiaxin Lin, Huayong Yang, Hongzhao Zhou   +4 more
wiley   +1 more source

Investigation of deformation characteristics of gate and earth-rock dam systems under deep overburden conditions. [PDF]

Sci Rep
Liu B, Wang F, Zou D, Zhuo Y, Pang S.
europepmc   +1 more source

Fundamental Challenges, Physical Implementations, and Integration Strategies for Ising Machines in Large‐Scale Optimization Tasks

Advanced Electronic Materials, EarlyView.
Ising machines are emerging as specialized hardware solvers for computationally hard optimization problems. This review examines five major platforms—digital CMOS, analog CMOS, emerging devices, coherent optics, and quantum systems—highlighting physics‐rooted advantages and shared bottlenecks in scalability and connectivity.
Hyunjun Lee, Joon Pyo Kim, Sanghyeon Kim
wiley   +1 more source

Study on influence of cosine-shaped subgrade settlement at different positions on the deformation and interlayer contact behavior of unit slab ballastless track. [PDF]

Sci Rep
Tan J, Jiang X, Luo R, Li H, He S, Hou Y.   +5 more
europepmc   +1 more source