Results 101 to 110 of about 408,590 (264)

Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis

Hepatology, EarlyView., 2022
Diagram of the activation of the profibrotic and procontractile Janus kinase 2 (JAK2)/Ras homolog family member A/Rho‐kinase pathway and the inhibition of phosphorylated JAK2 by pacritinib to inhibit hepatic stellate cell activity. Abstract Background and Aims Janus kinase 2 (JAK2) signaling is increased in human and experimental liver fibrosis with ...
Sandra Torres, Cristina Ortiz, Nadine Bachtler, Wenyi Gu, Leon D. Grünewald, Nico Kraus, Robert Schierwagen, Christoph Hieber, Caroline Meier, Olaf Tyc, Maximilian Joseph Brol, Frank Erhard Uschner, Bart Nijmeijer, Christoph Welsch, Marie‐Luise Berres, Carmen Garcia‐Ruiz, Jose Carlos Fernandez‐Checa, Christian Trautwein, Thomas J. Vogl, Stefan Zeuzem, Jonel Trebicka, Sabine Klein   +21 more
wiley   +1 more source

Towards More Robust Nanobioscience: Launching the NanoBubbles Replication Initiative

Angewandte Chemie, EarlyView.
The NanoBubbles Reproducibility Initiative investigates the robustness of highly cited articles in nanobioscience. Here, we document the process of setting up the initiative from corpus creation to publishing results. We also present platforms that we adopted and challenges that we faced.
Maha Said, Mustafa Gharib, Raphaël Lévy   +2 more
wiley   +2 more sources

Ditched and walled enclosures in Prehistoric Iberia (4th-3rd millennia cal. BCE): Like oil and water

Lucentum
Iberian Copper Age «ditched» and «walled» enclosure sites are often thought to represent two clearly distinguishable groups of sites. However, the discovery of sites where both ditches and walls are present («mixed sites») complicates things.
Víctor Jiménez-Jáimez, Marcos García-García, Adara López-López, David W. Wheatley   +3 more
doaj   +1 more source

Unraveling Energy Flow Mechanisms in Semiconductors by Ultrafast Spectroscopy: Germanium as a Case Study

Advanced Science, EarlyView.
A multi‐technique pump‐probe setup capable of performing both transient reflectivity and time‐resolved Raman spectroscopy after ultrafast excitation, provides a comprehensive understanding of ultrafast electronic and phononic processes. Distinct decay rates for the temperature, frequency, and linewidth of the phonon mode in germanium are observed ...
Grazia Raciti, Begoña Abad, Riccardo Dettori, Raja Sen, Aswathi K. Sivan, Jose M. Sojo‐Gordillo, Nathalie Vast, Riccardo Rurali, Claudio Melis, Jelena Sjakste, Ilaria Zardo   +10 more
wiley   +1 more source

A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation

Hepatology, EarlyView., 2022
In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole, Kristin Kaasen Jørgensen, Kristian Holm, Peder R. Braadland, Malin Holm Meyer‐Myklestad, Asle Wilhelm Medhus, Dag Henrik Reikvam, Alexandra Götz, Krzysztof Grzyb, Kirsten Muri Boberg, Tom Hemming Karlsen, Martin Kummen, Johannes R. Hov   +12 more
wiley   +1 more source

La ampliación de la UE: éxito colectivo, peligro de autocomplacencia [PDF]

, 2004
Desde el pasado 1 de mayo la Unión Europea cuenta con 25 miembros. Sin embargo, no todos son motivos de celebraciones. La ampliación es un gran éxito colectivo que desmiente que la Unión Europea carezca de política exterior.
Torreblanca, José Ignacio
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Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance

Advanced Science, EarlyView.
DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin, Emma Perrot, Thibault Dhellemmes, Laura Boi, Daniel De Castro Medeiros, Christelle Glangetas, Sylvie Dumas, Sandra Dovero, Nathalie Biendon, Elodie Ladeveze, Maëlle Hardel, Marc Landry, Erwan Bezard, Jérôme Baufreton, Gilberto Fisone, François Georges   +15 more
wiley   +1 more source

Reflexiones sobre el futuro de la Unión Europea (II). Actualización del Informe del Gobierno al Congreso de los Diputados [PDF]

, 2007
Actualización del informe realizado por el Gobierno a petición de la Comisión Mixta Congreso-Senado para la Unión Europea en septiembre de 2005, tras las negativas francesa y holandesa al Tratado constitucional, publicado por el Real Instituto Elcano en ...

core  

Solution‐Shearing of Highly Smooth Ion‐Gel Thin Films: Facilitating the Deposition of Organic Semiconductors for Ion‐Gated Organic Field Effect Transistors

Advanced Electronic Materials, Volume 11, Issue 6, May 2025.
A straightforward method is introduced to produce ion‐gel films with very low surface roughness by employing a solution‐shearing coating process. These ion‐gel films permit the growth of crystalline thin films of various small molecule organic semiconductor molecules directly on top of the ion‐gel layer, thereby enabling “inverted” small molecule ...
Jonathan Perez Andrade, Angelika Wrzesińska‐Lashkova, Anupam Prasoon, Felix Talnack, Katherina Haase, Bernd Büchner, Xinliang Feng, Yana Vaynzof, Mike Hambsch, Yulia Krupskaya, Stefan C. B. Mannsfeld   +10 more
wiley   +1 more source

Negociaciones Mercosur-Unión Europea, articulación del espacio Euro-Latinoamericano/Caribeño y gobernanza mundial [PDF]

, 2006
El ISSN corresponde a la versión electrónica del documentoEl trabajo analiza las negociaciones Unión Europea-MERCOSUR y la articulación de las mismas con el proceso de Cumbres biregionales que protagonizan la Unión Europea con América Latina/Caribe.
Bizzozero Revelez, Lincoln
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