Results 161 to 170 of about 80,741 (259)

The regulatory frameworks surrounding CRISPR‐edited papaya and their impact on international commerce

Journal of the Science of Food and Agriculture, Volume 106, Issue 11, Page 6262-6270, 30 August 2026.
Abstract The papaya tree (Carica papaya L.), native to the Americas, is cultivated in tropical regions and holds substantial economic importance, with an estimated export volume of 365 000 t in 2023. However, diseases caused by viruses, fungi, bacteria, and nematodes can lead to severe losses.
Luíza Favaratto, Mirielson L da Silva, David S Buss, Oeber F Quadros, Raul Tapia‐Tussell, José A Ventura, Antonio Alberto R Fernandes, Patricia M B Fernandes   +7 more
wiley   +1 more source

[Sepsis in the Intermediate Respiratory Care Unit: Restrospective Study]. [PDF]

Open Respir Arch
Garcia Prieto F, López Padilla D, Durán Barata D, Abad Fernández A.   +3 more
europepmc   +1 more source

Optimizing safety and efficacy of asparaginase and blinatumomab therapy in frontline acute lymphoblastic leukemia regimens in diverse health care settings—international expert consensus

Cancer, Volume 132, Issue 16, 15 August 2026.
ABSTRACT Frontline blinatumomab combined with chemotherapy has resulted in improved outcomes in both pediatric and adult patients with acute lymphoblastic leukemia and is considered the new cornerstone of acute lymphoblastic leukemia treatment. The role of asparaginase in this new landscape of acute lymphoblastic leukemia treatment was extensively ...
Daniel J. DeAngelo, Anna Avagyan, Jeanine Alfaro, Valentino Conter, Maria L. de Martino Lee, Łukasz Hutnik, Miriam Hwang, Hiroto Inaba, Atsushi Manabe, Jae H. Park, Rob Pieters, Carmelo Rizzari, Vaskar Saha, David T. Teachey, Inge M. van der Sluis, Scott C. Howard   +15 more
wiley   +1 more source

Rational Design of Multifunctional Tacrine Derivatives as Candidates for the Treatment of Alzheimer and Parkinson Diseases

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
We present a set of multifunctional tacrine derivatives, designed with the CADMA‐Chem protocol, aimed for Alzheimer and Parkinson diseases. Of the tacrines designed, TAC‐674 and TAC‐678 are the best candidates to act as multifunctional antioxidants and neuroprotectors for Alzheimer and Parkinson diseases, respectively.
Eugenia Dzib, Luis Felipe Hernández‐Ayala, Silvana Silva‐Aguirre, Annia Galano   +3 more
wiley   +1 more source

Genomic epidemiology of carbapenemase-producing <i>Klebsiella pneumoniae</i> circulating in a Chilean tertiary-care hospital (2021-2022): Molecular characterization, resistance-virulence convergence, and clinical associations. [PDF]

Microb Cell
Araya G, Álvarez A, Arellano C, Bravo R, Gajardo A, Barrera B, Silva F, Vidal RM.   +7 more
europepmc   +1 more source

Mapping Trofinetide Polypharmacology in Rett Syndrome: A Multi‐Stage Computational Analysis

Journal of Computational Chemistry, Volume 47, Issue 21, August 5, 2026.
How can a single molecule address the complex symptoms of Rett syndrome? This computational study maps the multi‐target mechanism of trofinetide, revealing diverse modes of binding across five key receptors: GAT1, GABAA, CHRM1, AMPA, and GSK3β. From deep orthosteric anchoring to dynamic surface interactions, these structural insights provide a rational
Luis Felipe Hernández‐Ayala, Gabriel Eduardo Guzmán‐López, Annia Galano   +2 more
wiley   +1 more source

Does Exercise Overcome Pollution? Why Physical Activity is Still Our Best Medicine. [PDF]

Open Respir Arch
Cejudo Ramos P, Rivilla Rivilla R, Sayago Reza I.   +2 more
europepmc   +1 more source

Analysis of anxiety levels and perceived satisfaction after a first encounter with human body prosection among nursing undergraduates based on their self‐perceived presession nervousness: An observational study

Anatomical Sciences Education, Volume 19, Issue 8, Page 1238-1247, August 2026.
Abstract Human body prosection practices are a crucial educational tool for learning anatomy. However, the first exposure to donors' material can cause anxiety, which may affect students' learning experiences and emotional adjustment. This observational study aimed to analyze anxiety levels (state and trait) before and after a prosection session in ...
Mónica Grande‐Alonso, María Teresa García‐de Juan, Irene Méndez‐Mesón, Soledad Aguado‐Henche, Rafael Ramírez‐Carracedo, Roberto Fernández‐Baillo, Mauricio Hernández‐Fernández, Alba Sebastián‐Martín, Rafael Moreno‐Gómez‐Toledano   +8 more
wiley   +1 more source

Extent, characteristics and policy applications of Key Biodiversity Areas

Biological Reviews, Volume 101, Issue 4, Page 1735-1759, August 2026.
ABSTRACT A global standard for the identification of Key Biodiversity Areas (KBAs) was published 10 years ago to provide a unified set of criteria for identifying ‘sites of significance for the global persistence of biodiversity’. We review the initiative's origins, the KBA identification process, characteristics of the current network, threats, policy
Stuart H. M. Butchart, Olivia Crowe, Tom Scott, Andrew J. Plumptre, Megan Eldred, Ellen McKee, Zoltan Waliczky, Ibrahim Al Hasani, Adrián B. Azpiroz, Daniele Baisero, Fred Barasa, Alison E. Beresford, Bezeng S. Bezeng, Charlotte Boyd, Thomas M. Brooks, Graeme Buchanan, Gill Bunting, Sofia Capellan, Neil Cox, Tim R. B. Davenport, Tammy E. Davies, Gina Della Togna, Wendy Elliott, Matt Foster, Jo Gilbert, Jonathan M. Handley, Diego Juffe‐Bignoli, Victoria R. Jones, Naomi Kingston, Jeannot Kivono, John Lamoreux, Penny F. Langhammer, James Lewis, Bruce Liggitt, Daniel Marnewick, Paul Matiku, Erin McCreless, Rachel A. Neugarten, Catherine Numa, Mark O'Brien, Madhu Rao, Ciara Raudsepp‐Hearne, Justina C. Ray, Samridhi Rijal, Jon Paul Rodríguez, Jurgis Sapijanskas, Wes Sechrest, Martin Sneary, Andrew Snyder, Konstantina Spiliopoulou, Thomas Starnes, Cecilia Tobar, Gautam Surya, Marcelo F. Tognelli, Andrew W. Tordoff, Maria G. Toscano, Yongyut Trisurat, Amy Upgren   +57 more
wiley   +1 more source

Efavirenz-Altered Gut-Microbiota, <i>Tph1</i>, and Systemic 5-HT Levels: Could They Affect Depression Mechanisms in Mice? [PDF]

Int J Mol Sci
Rojas-Osornio SA, Paredes-Cervantes V, Aguirre-García MM, Crespo-Ramírez M, Márquez-Mota CC, Aguilar-Rosales R, Talamantes-Gómez JM, Escalona-Montaño AR, García-Pérez Á, Pérez de la Mora M, Borroto-Escuela DO, Manuel-Apolinar L, Pérez-Sánchez G, Vazquez-Vega S, Martínez-Lara R, Tesoro-Cruz E.   +15 more
europepmc   +1 more source