Results 41 to 50 of about 99,447 (295)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Optimal design of the cable metro with unified intermediate supports [PDF]
In article was formulated and solved the problem of conditional nonlinear technical and economic optimization of the distance between intermediate supports, uniform in height, during the design of the cable metro lines in highly urban-ized city ...
Lagerev A.V., Lagerev I.A.
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Unification of Higher-order Patterns modulo Simple Syntactic Equational Theories [PDF]
We present an algorithm for unification of higher-order patterns modulo simple syntactic equational theories as defined by Kirchner [14]. The algorithm by Miller [17] for pattern unification, refined by Nipkow [18] is first modified in order to behave as
Alexandre Boudet
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Perimeter-Minimizing Triple Bubbles in the Plane and the 2-Sphere
We use continuous and discrete unification to prove that standard triple bubbles in ℝ2 and 𝕊2 are the minimizers of perimeter, among all clusters (Definition 2.3) enclosing the same triple of areas.
Lawlor Gary R.
doaj +1 more source
String Phenomenology: Past, Present and Future Perspectives
The observation of a scalar resonance at the Large Hadron Collider (LHC), compatible with perturbative electroweak symmetry breaking, reinforces the Standard Model (SM) parameterisation of all subatomic data. The logarithmic evolution of the SM gauge and
Alon E. Faraggi
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Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

