Results 41 to 50 of about 99,447 (295)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Optimal design of the cable metro with unified intermediate supports [PDF]

open access: yesНаучно-технический вестник Брянского государственного университета, 2017
In article was formulated and solved the problem of conditional nonlinear technical and economic optimization of the distance between intermediate supports, uniform in height, during the design of the cable metro lines in highly urban-ized city ...
Lagerev A.V., Lagerev I.A.
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Unification of Higher-order Patterns modulo Simple Syntactic Equational Theories [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2000
We present an algorithm for unification of higher-order patterns modulo simple syntactic equational theories as defined by Kirchner [14]. The algorithm by Miller [17] for pattern unification, refined by Nipkow [18] is first modified in order to behave as
Alexandre Boudet
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Perimeter-Minimizing Triple Bubbles in the Plane and the 2-Sphere

open access: yesAnalysis and Geometry in Metric Spaces, 2019
We use continuous and discrete unification to prove that standard triple bubbles in ℝ2 and 𝕊2 are the minimizers of perimeter, among all clusters (Definition 2.3) enclosing the same triple of areas.
Lawlor Gary R.
doaj   +1 more source

String Phenomenology: Past, Present and Future Perspectives

open access: yesGalaxies, 2014
The observation of a scalar resonance at the Large Hadron Collider (LHC), compatible with perturbative electroweak symmetry breaking, reinforces the Standard Model (SM) parameterisation of all subatomic data. The logarithmic evolution of the SM gauge and
Alon E. Faraggi
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Unification theory

open access: yesJournal of Symbolic Computation, 1989
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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