Results 31 to 40 of about 5,847 (262)

From Aesthetic Virtues to God:

open access: yesTheoLogica, 2023
I argue that the aesthetic theoretical virtues of beauty, simplicity, and unification, as well as the evidential virtue of explanatory depth, can transform theistic-friendly personal cause (PC) arguments—like the kalām cosmological argument (KCA) and ...
Rad Miksa
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Unification modulo a 2-sorted Equational theory for Cipher-Decipher Block Chaining [PDF]

open access: yesLogical Methods in Computer Science, 2014
We investigate unification problems related to the Cipher Block Chaining (CBC) mode of encryption. We first model chaining in terms of a simple, convergent, rewrite system over a signature with two disjoint sorts: list and element.
Siva Anantharaman   +3 more
doaj   +1 more source

On unification: Equational theories are not bounded

open access: yesJournal of Symbolic Computation, 1986
We are interested in first-order unification problems and, more specifically, in the hierarchy of equational theories based on the cardinality of the set of most general unifiers. The following result is established in this paper: if T is a suitable first-order equational theory that is not unitary, then T is not bounded; that is, there is no integer \(
Ronald V. Book, Jörg H. Siekmann
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

On equational theories, unification and decidability [PDF]

open access: yes, 1987
The following classes of equational theories, which are important in unification theory, are presented: permutative, finite, Noetherian, simple, almost collapse free, collapse free, regular, and Ω-free theories. The relationships between the particular theories are shown and the connection between these classes and the unification hierarchy is pointed ...
Hans-Jürgen Bürckert   +2 more
openaire   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Unification and Anti-unification modulo Equational Theories

open access: yesEPiC Series in Computing, 2018
Automated reasoning modulo an equational theory E is a fundamental technique in many applications. In this talk, we would present a narrowing-based equational unification algorithm for theories satisfying the finite variant property.
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A Concurrent Pattern Calculus [PDF]

open access: yesLogical Methods in Computer Science, 2014
Concurrent pattern calculus (CPC) drives interaction between processes by comparing data structures, just as sequential pattern calculus drives computation.
Thomas Given-Wilson   +2 more
doaj   +1 more source

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