Results 181 to 190 of about 1,898 (226)

An in-depth transcriptomic atlas deciphering traditional Chinese medicine mechanisms and disease associations. [PDF]

Sci Data
Zhao H, Ben P, Liu Z, Guan M, Lin L, Han D, Guo J, Wang L.   +7 more
europepmc   +1 more source

Accurately Deciphering Tissue Heterogeneity From Spatial Multi‐Modal and Multi‐Omics With STransformer

Advanced Science, EarlyView.
STransformer is a unified deep learning framework designed to seamlessly accommodate a comprehensive landscape of spatial data. By simultaneously capturing short‐range cellular interactions and tissue‐wide semantic patterns, it extracts robust representations to accurately dissect complex tissue heterogeneity.
Xingyi Li, Jialuo Xu, Gaoyuan Du, Xiangting Jia, Dongmin Zhao, Chunyan Zhou, Kexin Xiao, Jia Gu, Junnan Zhu, Xuequn Shang   +9 more
wiley   +1 more source

An ontology-driven knowledge graph for tourism information management. [PDF]

Open Res Eur
DAS S, Bagchi M.
europepmc   +1 more source

Epidermal METTL1‐Mediated m7G Modification Drives Psoriatic Inflammation by Stabilizing Bdkrb1 and Orchestrating Neutrophil Recruitment

Advanced Science, EarlyView.
This study unveils an unrecognized pro‐inflammatory epitranscriptomic checkpoint in psoriasis. By installing m7G modifications on the 5′ UTR of Bdkrb1 mRNA, METTL1 enhances receptor stability to orchestrate keratinocyte‐driven neutrophil recruitment via p38 MAPK signaling.
Chang Zhang, Jiayi Lu, Sihao Yan, Yirui Wang, Zhuo Li, Weiwei Chen, Yang Han, Ziyan Zhang, Yafen Yu, Qi Zhen, Liangdan Sun   +10 more
wiley   +1 more source

Research information systems and knowledge graphs: a review. [PDF]

Front Res Metr Anal
Haris M, Auer S, Stocker M.
europepmc   +1 more source

Cholesterol‐Mediated Metabolic‐mechanotransductive Crosstalk Orchestrates Castration Resistance in Prostate Cancer

Advanced Science, EarlyView.
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu, Chao Xu, Jun Jiang, Limin He, Yike Zhou, Zhengxuan Li, Yu Li, Keying Zhang, Fa Yang, Tong Lu, Hongtao Song, Hai Zhu, Zhihao Hu, Xiaolong Zhao, Kai Gan, Hongji Li, Bo Yang, Rui Zhang, Weihong Wen, Donghui Han, Weijun Qin   +20 more
wiley   +1 more source

Toward a unified vocabulary for embodiment research challenges and solutions. [PDF]

NPJ Sci Learn
Wang P, Li J, Yu Q, Zou L, Xu X, Mavilidi M, Falck RS, Herold F, Schinke RJ, Raab M, Paas F.   +10 more
europepmc   +1 more source

Desiderata for a biomedical knowledge network: opportunities, challenges and future directions. [PDF]

Bioinform Adv
Wu C, Liu H, Flannick J, Musen MA, Su AI, Hunter LE, Powers TM, Wu CH.   +7 more
europepmc   +1 more source

BioOne: a national-scale platform for integrated discovery and utilization of diverse biological resources in South Korea. [PDF]

Genomics Inform
Kang TH, Ha K, Kyung W, Jeon YJ, Jo GH, Park K, Lee K, Jin TE.   +7 more
europepmc   +1 more source

An adaptive semantic retrieval framework for digital libraries integrating graph neural networks, ontology, and user behavior. [PDF]

Sci Rep
Bi R.
europepmc   +1 more source