Results 11 to 20 of about 1,898 (226)

Toward an Ontology of Wargame Design

IEEE Access
Governments rely on military power to address conflicts, manage crises, and adapt to the evolving nature of modern warfare, which is often characterized by uncertainty and disorder.
Leandro Ouriques, Carlos Eduardo Barbosa, Joshua Kritz, Geraldo Xexeo   +3 more
doaj   +1 more source

A Lightweight Ontology for Enterprise Architecture Mining of API Gateway Logs

IEEE Access
Enterprise Architecture (EA) is defined as a set of principles, methods, and models that support the design of organizational structures, expressing the different concerns of a company and its IT landscape, including processes, services, applications ...
Carlos Roberto Pinheiro, Sergio Luis Proenca Duarte Guerreiro, Henrique S. Mamede   +2 more
doaj   +1 more source

Knowledge Representation Method for Grotto Buddhist Niches Based on Image Semantics and Ontology

Buildings
Grotto Buddhist Niches are important spatial carriers of Buddhist cave art, containing rich architectural, artistic, and historical information. However, image data of these Buddhist niches are fragmented across multiple scales, including visual features,
Li Wan, Miaole Hou, Jinru Li, Beibei Zhao, Bingyu Yang, Haoyue Shi, Bo Ning   +6 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Cognitive Digital Twin Generations: From Foundational Instruments to Meta-Cognitive Ecosystems

Information
The growing complexity of cyber-physical and socio-technical systems calls for digital twin architectures capable of modeling cognition-driven processes such as perception, reasoning, learning, and reflection.
Igor Kabashkin
doaj   +1 more source

A Comparative Study of Ghiyath al-Din Dashtaki’s and Ayatollah Javadi Amoli’s Views on the Factors of Spiritual Wayfaring from a Foundational Perspective [PDF]

Comparative Theology
The spiritual journey in Islamic wisdom aims at reaching the highest stage of perfection, which is direct intuitive knowledge of the Divine Reality. Achieving this goal demands accurate cognition, spiritual refinement, and guidance under a qualified ...
Mehri Mehrabi Fodani, Sayyed Hossain Vaezi, Azam Rejali   +2 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

OSDBA: A Bilingual Ontology for the Representation of Shang Dynasty Bronze Artifacts With Archaeometallurgical Knowledge

IEEE Access
The bronze artifacts of the Shang Dynasty serve as pivotal carriers of early Chinese civilization’s technological and cultural achievements, with their intricate classification systems and multidimensional attributes (e.g., metallurgical ...
Meng Jiang, Huiru Lian, Chenyuan Li, Mingyu Huang, Kunlong Chen   +4 more
doaj   +1 more source