Results 131 to 140 of about 309,244 (268)
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown +6 more
wiley +1 more source
Enhancing Medical Image Retrieval with UMLS-Integrated CNN-Based Text Indexing
DiagnosticsIn recent years, Convolutional Neural Network (CNN) models have demonstrated notable advancements in various domains such as image classification and Natural Language Processing (NLP).
Karim Gasmi, Hajer Ayadi, Mouna Torjmen
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu +10 more
wiley +1 more source
HeliyonA transient ischemic attack (TIA) affects millions of people worldwide. Although TIA risk factors have been identified individually, a systemic quantitative analysis of all health factors relevant to TIA using electronic medical records (EMR) remains ...
Jian Wen +8 more
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FDG‐PET Associations With Disease Severity and Outcomes in NMDA‐Receptor IgG Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Patients with N‐methyl‐D‐aspartate (NMDA) receptor‐immunoglobulin G (IgG) autoimmune encephalitis (NMDAR‐IgG AE) demonstrate occipital lobe hypometabolism on baseline brain fluorodeoxyglucose‐positron emission tomography (bFDG‐PET).
Jonathan K. Lee +7 more
wiley +1 more source
Multilabel Classification of Radiology Image Concepts Using Deep Learning
Applied SciencesUnderstanding and interpreting medical images, particularly radiology images, is a time-consuming task that requires specialized expertise. In this study, we developed a deep learning-based system capable of automatically assigning multiple standardized ...
Vito Santamato, Agostino Marengo
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Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang +10 more
wiley +1 more source
RECIIS, 2009 This paper provides a survey of the state of the art in terminologies and ontologies applied to Biology and Medicine. Not intending to be fully comprehensive, we describe some of the most relevant resources that currently attract interest from industry ...
Frederico Freitas +2 more
doaj
The impact of learning Unified Medical Language System knowledge embeddings in relation extraction from biomedical texts. [PDF]
J Am Med Inform Assoc, 2020 Weinzierl MA, Maldonado R, Harabagiu SM.
europepmc +1 more source