Results 71 to 80 of about 245,364 (303)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A study on psychological determinants of users' autonomous vehicles adoption from anthropomorphism and UTAUT perspectives

Frontiers in Psychology, 2022
As the autonomous vehicles technology gradually enters the public eye, understanding consumers' psychological motivations for accepting autonomous vehicles is critical for the development of autonomous vehicles and society.
Yuqi Tian, Xiaowen Wang
doaj   +1 more source

Awareness of wireless sensor network potential in healthcare industry: A second UTAUT study [PDF]

, 2006
This study concentrates on investigating the degree of awareness, future adoption and uptake of wireless sensor networks (WSNs) (in particular Motes) in the Health Monitoring arena via the use of our second Web-based survey.
Lawrence, E, Lubrin, E, Navarro, KF, Zmijewska, A   +3 more
core  

What factors determine therapists’ acceptance of new technologies for rehabilitation – a study using the Unified Theory of Acceptance and Use of Technology (UTAUT)

Disability and Rehabilitation, 2014
Purpose: The aim of this study was to examine what factors affect the acceptance behavior and use of new technologies for rehabilitation by therapists at a large rehabilitation hospital in Canada. Method: A self-administrated paper-based survey was created by adapting scales with high levels of internal consistency in prior research using the Unified ...
Lili Liu, Antonio Miguel-Cruz, Adriana Ríos Rincón, Vickie Buttar, Quentin Ranson, Darrell Goertzen   +5 more
openaire   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Health information systems to improve health care: A telemedicine case study

South African Journal of Information Management, 2013
Background: E-health has been identified as an integral part of the future of South Africanpublic healthcare. Telemedicine was first introduced in South Africa in 1997 and since thenthe cost of running the Telemedicine projects has increased ...
Liezel Cilliers, Stephen V. Flowerday
doaj   +3 more sources

Enhancing the acceptance of smart sensing in psychotherapy patients: findings from a randomized controlled trial

Frontiers in Digital Health
ObjectiveSmart sensing has the potential to make psychotherapeutic treatments more effective. It involves the passive analysis and collection of data generated by digital devices.
Fabian Rottstädt, Fabian Rottstädt, Eduard Becker, Gabriele Wilz, Ilona Croy, Ilona Croy, Harald Baumeister, Harald Baumeister, Yannik Terhorst, Yannik Terhorst, Yannik Terhorst, Yannik Terhorst   +11 more
doaj   +1 more source

Demand for Mobile Health in Developing Countries During COVID-19: Vietnamese’s Perspectives from Different Age Groups and Health Conditions

Patient Preference and Adherence, 2022
Hung Long Nguyen,1,2,* Khoa Tran,1,* Phuong Le Nam Doan,1,2,* Tuyet Nguyen1,3,* 1Department of Youth Lab for Social Innovation, MiYork Research, Ho Chi Minh City, Vietnam; 2Department of Biology, Vietnam National University Ho Chi Minh ...
Nguyen HL, Tran K, Doan PLN, Nguyen T
doaj  

Ridesharing in the Polish Experience: A Study using Unified Theory of Acceptance and Use of Technology

Central European Economic Journal, 2020
Abstract The main aim of this article is to examine the factors that influence the acceptance of ridesharing technologies in Polish society, including dynamic vanpooling on demand. The study was conducted using the UTAUT 2 model (Theory of Acceptance and Use of Technology).
Stefan Cylwik, Renata Gabryelczyk, Marcin Chlebus   +2 more
openaire   +2 more sources