Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng
Molood Behbahanipour +11 more
wiley +1 more source
Variational structures for the Fokker-Planck equation with general Dirichlet boundary conditions. [PDF]
Quattrocchi F.
europepmc +1 more source
A robust zinc‐based metal–organic framework (ZnMOF) enables dual functions of doxorubicin delivery and sustained Zn2+ release to trigger ferroptosis‐enhnaced chemotherapy. DOX@ZnMOF effectively depletes intracellular glutathione, suppresses GPX4, and elevates reactive oxygen species, leading to efficient oxidative DNA damage and apoptosis.
Xin Ma +5 more
wiley +1 more source
Research on a multivariate measurement system for polyethylene gas pipelines utilizing a variable weight UMAP model. [PDF]
Zong C +5 more
europepmc +1 more source
Artificial neural network paradigm of magneto-thermal behavior in tangent hyperbolic hybrid-nanofluid flow. [PDF]
Athar T, Qureshi H, Muhammad T.
europepmc +1 more source
Multi-Factor Cost Function-Based Interference-Aware Clustering with Voronoi Cell Partitioning for Dense WSNs. [PDF]
Sam Peter S +3 more
europepmc +1 more source
Green supply chain management and coordinated optimization by an improved sparrow search algorithm. [PDF]
Wang G.
europepmc +1 more source
Meta-analysis models relaxing the random-effects normality assumption: methodological systematic review and simulation study. [PDF]
Panagiotopoulou K +4 more
europepmc +1 more source

