During renal fibrosis, SMAD3 acts as a transcription factor for CRLF1, promoting its expression and secretion. CRLF1 then binds to ITGB1 via an autocrine mechanism, activating the PI3K‐AKT signaling pathway to mediate renal fibrosis. This accelerates the progression from AKI to CKD, highlighting the therapeutic potential of targeting CRLF1 for ...
Chunjie Wang +8 more
wiley +1 more source
Updatable Closed‐Form Evaluation of Arbitrarily Complex Multiport Network Connections
The inverse design of electrically large wave devices often uses reduced‐order multiport models with discrete optimization, requiring many evaluations of complex interconnections between subsystems that differ only in a few blocks. This paper introduces a closed‐form framework enabling efficient Woodbury low‐rank updates of related, previous ...
Hugo Prod'homme, Philipp del Hougne
wiley +1 more source
Comparison of Bilateral and Unilateral Applications of Percutaneous Vertebroplasty and Kyphoplasty Procedures. [PDF]
Serpi M, Çakan A, Akpınar A.
europepmc +1 more source
Keeping Pace or Falling Behind? The Depth of Latin American Trade Agreements
ABSTRACT This article examines whether Latin American countries are keeping pace with global trends in trade agreement depth or falling behind. Using 681 agreements (1970–2019), we develop the Depth Index of Trade Agreements (DITA) to weight provisions endogenously through factor analysis based on co‐occurrence patterns.
Raphael Gomes da Silva +2 more
wiley +1 more source
Dynamic Digital Radiography for Functional Assessment of Unilateral Main Bronchial Stenosis Before and After Treatment: A Case Report. [PDF]
Tsuruoka H +6 more
europepmc +1 more source
ABSTRACT This paper explores Swedish consumers' protein preferences by estimating the willingness‐to‐pay (WTP) for minced meat and plant‐based proteins in pasta sauce from an in‐store experiment (n = 206) and an online discrete choice experiment (n = 517). On average, the WTP was highest for minced meat.
Emilia Mattsson +3 more
wiley +1 more source
Does exercising bilaterally require measuring bilaterally? Bilateral versus unilateral tourniquet cuff inflation during measurement of arterial occlusion pressure: considerations for blood flow restriction exercise. [PDF]
Bielitzki R +6 more
europepmc +1 more source
ABSTRACT Background Erectile dysfunction (ErD) is an important complication after rectal cancer surgery, however a substantial proportion of patients experience functional recovery over time. Evidence regarding which patients are more likely to recover remains limited.
Ryosuke Mizuno +21 more
wiley +1 more source
The role of attachment type and bone height in modulating stress distribution in mandibular overdentures: Insights from finite element analysis. [PDF]
Gencel Bİ +4 more
europepmc +1 more source

