Results 121 to 130 of about 847,240 (265)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Intramedullary Nailing for Segmental Tibia Fractures: A Comprehensive Retrospective - Prospective Outcome Analysis in 30 Patients at a Tertiary Care Centre. [PDF]

J Orthop Case Rep
Thirunthaiyan MR, Velmurugan P, Rohinth S, Kumar RD, Sundararaja B.   +4 more
europepmc   +1 more source

Unions

, 2020
openaire   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Interactions (socio) sémiotiques

Actes Sémiotiques, 2017
Eric Landowski
doaj   +1 more source

Rate of fibular non-union in patients with tibial shaft fractures: a retrospective cohort study. [PDF]

Eur J Orthop Surg Traumatol
Day WA, Clark CJ, Riley JW, Melancon DP, Spears IJ, Davidson JC, Hopper L, Parker RP, Nehete P, Mittwede PN, Bergin PF.   +10 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Here today, gone tomorrow: the transformative role of biodegradable materials in modern trauma care. [PDF]

EFORT Open Rev
Marta M, Machado PM, Oliveira L, Marcos Miranda I, Vaz MF, Costa de Oliveira S.   +5 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Closed-Set Heterogeneous Domain Adaptation for IoT Intrusion Detection: An Anchor-Based Benchmark Across Single- and Multi-Source Transfer. [PDF]

Sensors (Basel)
Chizari M, Khan Ali Mirza Q, Alam A, Chizari H.   +3 more
europepmc   +1 more source