Results 121 to 130 of about 5,203,932 (313)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
READOUT OF THE PHONE CALL BETWEEN THE CHAIRPERSON OF THE AFRICAN UNION COMMISSION AND THE UNITED STATES SECRETARY OF STATE [PDF]
, 2018 Addis Ababa, 18 May 2018: African Union Commission Chairperson Moussa Faki Mahamat and U.S. Secretary of State Mike Pompeo had a telephone conversation today.
African Union
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Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Union white flash road map of New South Wales [cartographic material].
, 1932 5th ed., rev. Road map of New South Wales.; "231020".; "Map No. 212".; Includes list of places of historic interest and mileage tables.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.map-vn4604932.
Atlantic Union Oil Company.
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Report of the commission on the implementation of the assembly decision Assembly/AU/Dec.605 (XXVII) on the financing of the union [PDF]
, 2017 Assembly of the union twenty eighth ordinary session 30 - 31 January 2017 Addis Ababa ...
African Union, Africa union
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