Results 51 to 60 of about 1,133,829 (278)

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Romania - New E.U. Member State, A New Phase of Its Transition

open access: yesTransylvanian Review of Administrative Sciences, 2011
Ever since Romania started its transition in the 1990s, it consistently scored poorly in various comparative performance assessments aimed at rating developing countries.
Marius PROFIROIU   +3 more
doaj  

Albania: A Closer Look at Scientific Research Challenges

open access: yesActa Universitatis Danubius: Administratio, 2023
Scientific research is very important for the development of every country and, moreover, for the progress of a developing country with long delays in its development that also aspires to be a member of the European Union.
Rudina Lipi, Ilirjan Lipi, Evis Kumi
doaj  

Considerațiuni asupra domeniuliu forestier al României [Considerations on the Forestry of Romania] [PDF]

open access: yesBucovina Forestieră, 2018
Marin D. Drăcea was the most important personality of Romanian forestry from the interwar period, who had many exceptional results during his life. One of his achievement was the degree received in 1923 with „Summa cum laude” of the Ph.D.
Drăcea M.D.
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Problem konsolidacji współczesnego państwa macedońskiego w kontekście jego aspiracji do Unii Europejskiej

open access: yesSlavia Meridionalis, 2015
The issue оf contemporary Macedonian state consolidation in the context of its aspiration to the European Union Since its establishment, the Republic of Macedonia has been facing the crisis of social and political system.
Jędrzej Paszkiewicz
doaj   +1 more source

European and international policy agendas on children, youth and children's rights: a Belgian EU presidency-youth note [PDF]

open access: yes, 2010
This Presidency document describes the state of play of the European and international policy agendas on children, youth and children’s ...
Desmet, Ellen
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

A European army: so near and yet so far

open access: yesRevista CIDOB d'Afers Internacionals
It has been seven decades since the six founding member states of what would become the European Union (EU) sought to integrate their armies into a common defence force through the European Defence Community.
Rafa Martínez   +3 more
doaj   +1 more source

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