Results 41 to 50 of about 463,649 (305)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Diagnosis and treatment of iron deficiency in medical inpatients at a Swiss tertiary university referral hospital: a retrospective observational cohort study of clinical practice

Swiss Medical Weekly, 2013
BACKGROUND: Iron deficiency anaemia is a common disease with a prevalence of up to 19.2% in populations at risk. However, the prevalence of iron deficiency (ID) in hospitalised patients is not well known.
Balthasar L Hug, André Tichelli, Pascal Benkert, Guido Stirnimann, Juerg A Schifferli   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Evaluating a Bayesian approach to improve accuracy of individual photographic identification methods using ecological distribution data [PDF]

Computational Ecology and Software, 2011
Photographic identification of individual organisms can be possible from natural body markings. Data from photo-ID can be used to estimate important ecological and conservation metrics such as population sizes, home ranges or territories.
Richard Stafford, Jane R. Lloyd
doaj  

Managing diabetic foot infections: a survey of Australasian infectious diseases clinicians

Journal of Foot and Ankle Research, 2018
Background Diabetic foot infections (DFI) present a major morbidity, mortality and economic challenge for the tertiary health sector. However, lack of high quality evidence for specific treatment regimens for patients with DFIs may result in inconsistent
Robert J. Commons, Edward Raby, Eugene Athan, Hasan Bhally, Sharon Chen, Stephen Guy, Paul R. Ingram, Katy Lai, Chris Lemoh, Lyn-Li Lim, Laurens Manning, Spiros Miyakis, Mary O’Reilly, Adam Roberts, Marjoree Sehu, Adrienne Torda, Mauro Vicaretti, Peter A. Lazzarini   +17 more
doaj   +1 more source

A Topology-Based Local Identifier Mapping Scheme for Power System Resources in Common Information Model Framework for Interoperability

Applied Sciences, 2023
The Common Information Model (CIM) defined in international electrotechnical commission technical committee 57 (IEC TC57) has been utilized for achieving interoperability by employing a canonical data model strategy for standardizing interfaces in the ...
Jin-Uk Song, Jae-Guk An, Seong-Il Lim, Yun-Sik Oh   +3 more
doaj   +1 more source

Do we need a Unique Scientist ID for publications in biomedicine? [PDF]

Biomedical Digital Libraries, 2005
Abstract Background The PubMed database contains nearly 15 million references from more than 4,800 biomedical journals. In general, authors of scientific articles are addressed by their last name and forename initial. Discussion In general, names can be too common and not ...
Bohne-Lang, Andreas, Lang, Elke
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Implementing telemedicine with 5G technologies in a nursing home for reducing emergency admissions– study protocol of a mixed-methods study

BMC Health Services Research
Background By transmitting various types of data, telemedical care enables the provision of care where physicians and patients are physically separated.
Johanna Sophie Lubasch, Patrick Andreas Eder, Christian Kaiser, Andrea Diana Klausen, Daniel Overheu, Anja Partheymüller, Asarnusch Rashid, Simon Thomas Schäfer, Maximilian Scharonow, Insa Seeger   +9 more
doaj   +1 more source

Multifactorial determinants of cardiovascular disease: The role of socio-demographic, lifestyle, and morbidity factors

Journal of Education and Health Promotion
BACKGROUND: Cardiovascular disease (CVD) development was influenced by various factors, including socio-demographic aspects (age, gender, socioeconomic status, education), lifestyle behaviors (diet, physical activity, smoking, alcohol use), health ...
Sharada Ashok Jadhav, S. V. Kakade, Abhijeet B. Shelke, Satyajeet Ashok Jadhav, Sheela D. Kadam   +4 more
doaj   +1 more source