Results 131 to 140 of about 6,496,433 (308)
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Continuous dependence of solutions for indefinite semilinear elliptic problems
Electronic Journal of Differential Equations, 2013 We consider the superlinear elliptic problem $$ -\Delta u + m(x)u = a(x)u^p $$ in a bounded smooth domain under Neumann boundary conditions, where $m \in L^{\sigma}(\Omega)$, $\sigma\geq N/2$ and $a\in C(\overline{\Omega})$ is a sign changing ...
Elves A. B. Silva, Maxwell L. Silva
doaj
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Existence of a unique solution to an elliptic partial differential equation
Electronic Journal of Differential Equations, 2019 The purpose of this article is to prove the existence of a unique classical solution to the quasilinear elliptic equation $-\nabla \cdot(a(u) \nabla u)=f$ for $\mathbf{x} \in \Omega$, which satisfies the condition that $u(\mathbf{x}_0)=u_0$ at a ...
Diane L. Denny
doaj
Unconstrained image reconstruction with resolution modelling does not have a unique solution. [PDF]
EJNMMI Phys, 2014 Nuyts J.
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Optimal solution of nonlinear equations [PDF]
, 1985 journal articleWe survey recent worst case complexity results for the solution of nonlinear equations. Notes on worst and average case analysis of iterative algorithms and a bibliography of the subject are also ...
Optimal solution; Nonlinear equations +1 more
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source