Results 211 to 220 of about 6,496,433 (308)

Facile synthesis of surface-functionalized C₆₀ micro-rods and their humidity sensing potential. [PDF]

RSC Adv
Wang J, Du M, Guo L, Jia W, Li Z, Ma Y, Ma C, Yi X, Wang J.   +8 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

SNPoptimizer: a scalable genetic-algorithm framework to derive minimal discriminatory SNP panels from large genotyping datasets. [PDF]

Mol Breed
Esposito S, Scalzi N, Palombieri S, Sanseverino W, Sestili F, Stella A, Balestrini R, Grillo S, Bressan RA, Batelli G.   +9 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Serial Knockout Isolation Technique (SKIT): targeted isolation of multi-antagonist bacteria. [PDF]

MethodsX
Maheshwari HS, Gour A, Rajput LS, Kumar S, Shiv A, Parmar D, Solanki P, Bright JP, Singh RK, Sharma MP.   +9 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Novel Optical Sensor-Based Organic Chromophore for the Detection of Copper Ions. [PDF]

Biosensors (Basel)
Ali R, Almotiri MK, Messaoudi S, Ali IAI, Algreiby A, Saleh SM.   +5 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Rapid Fabrication of Capillary-Sized Microchannels in Collagen Hydrogel via Thermally Responsive Gelatin Microfiber Templates. [PDF]

Materials (Basel)
Takei T, Nakamura M, Nishimura K, Kobaru S, Ohzuno Y, Yoshida M.   +5 more
europepmc   +1 more source