Results 121 to 130 of about 5,110,699 (336)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Compressed Air Energy Storage-Part II: Application to Power System Unit Commitment

, 2017
Unit commitment (UC) is one of the most important power system operation problems. To integrate higher penetration of wind power into power systems, more compressed air energy storage (CAES) plants are being built.
Ansari, Osama Aslam, Chung, C. Y., Wen, Yunfeng, Zhan, Junpeng   +3 more
core  

Unit Commitment Solution Methods

, 2007
{"references": ["A. I. Cohen and V. R. Sherkat, \"Optimization based methods for\noperations scheduling\", Proceedings of the IEEE, vol. 75, no. 12, pp.\n1574-1591, 1987.", "S. K. Tong and S. M. Shahidehpour, \"An innovative approach to\ngeneration scheduling in large-scale hydro-thermal power systems with\nfuel constrained units\", IEEE Trans.
openaire   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Penerapan Batas Ramp-Rate dengan Menggunakan Kombinasi Metode FDP (Forward Dynamic Programming) dan QP (Quadratic Programming) Pada Unit Commitment-Economic Dispatch

Jurnal Teknik ITS, 2017
Kebutuhan akan energi listrik terus menigkat seiring dengan perkembangan teknologi. meningkatnya beban listrik ini harus diimbangi dengan penambahan daya yang dibangkitkan. Hal ini sangat berpengaruh pada penjadwalan unit pembangkit yang harus ditentukan
Riza Fahmi Andriyanto, Ontoseno Penangsang, Ni Ketut Aryani   +2 more
doaj  

A Data-Driven Model of Virtual Power Plants in Day-Ahead Unit Commitment

IEEE Transactions on Power Systems, 2019
Due to the increasing penetration of distributed energy resources (DERs), power system operators face significant challenges of ensuring the effective integration of DERs.
Sadra Babaei, Chaoyue Zhao, Lei Fan
semanticscholar   +1 more source

Large-scale decentralized unit commitment

International Journal of Electrical Power & Energy Systems, 2015
Abstract A method for formulating and solving a decentralized unit commitment problem is presented in this work. The method, which extends the alternating direction method of multipliers (ADMM), is presented along with several heuristics and refinements to mitigate oscillations and traps in local optimality that result from the nonconvexity of unit ...
Mohammad Javad Feizollahi, Mitch Costley, Shabbir Ahmed, Santiago Grijalva   +3 more
openaire   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source