Results 21 to 30 of about 31,137 (223)

Investigation of the Cross-Cutting Polycrystalline Diamond Compact Bit Drilling Efficiency

open access: yesShock and Vibration, 2021
The parallel track scraping principle of conventional PDC bits largely limits the cutting efficiency and working life in deep formations. Cross-cutting polycrystalline diamond compact (PDC) bit may be an efficient drilling tool that increases the rock ...
Chun-Liang Zhang   +5 more
doaj   +1 more source

Modelling of Oblique Wire Cutting and Experimental Application on Soft Solid Foods for the Investigation of Friction Behaviour

open access: yesJournal of Food Quality, 2019
The sales value of ready-made foods is determined to a large extent by the appearance of the individual pieces or slices. Breakouts or deformations are perceived negatively and should be avoided. The quality of the cut surface is derived as an evaluation
Tilman Witt   +3 more
doaj   +1 more source

A Comparison of the Probes with a Cantilever Beam and a Double-Sided Beam in the Tool Edge Profiler for On-Machine Measurement of a Precision Cutting Tool

open access: yesMachines, 2021
This paper describes a comparison of the mechanical structures (a double-sided beam and a cantilever beam) of a probe in a tool edge profiler for the measurement of a micro-cutting tool. The tool edge profiler consists of a positioning unit having a pair
Bo Wen   +6 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Experimental Study on Conglomerate Breaking Characteristics of Conical PDC Cutter

open access: yesShiyou jixie, 2021
In order to further improve the rock breaking efficiency and the adaptability of drilling hard and complex strata of PDC bit, a comprehensive test device of rock breaking by PDC cutter was developed. The test device was used to conduct experimental study
Xu Weiqiang   +6 more
doaj  

Multi-Objective Optimization for Milling Operations using Genetic Algorithms under Various Constraints [PDF]

open access: yesInternational Journal of Networked and Distributed Computing (IJNDC), 2014
In this paper, the parameter optimization problem for face-milling operations is studied. A multi-objective mathematical model is developed with the purpose to minimize the unit production cost and total machining time while maximize the profit rate. The
Libao An   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Experimentation and Analysis of Physical Properties Related to Quinoa Straws

open access: yesAgriEngineering
To study the cutting mechanical properties of quinoa straw and reduce the cutting force and unit area cutting power consumption of quinoa straw, this study took quinoa from low-altitude areas as the research object.
Bin Sun   +8 more
doaj   +1 more source

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