Results 131 to 140 of about 124,717 (298)

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

open access: yesAdvanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying   +8 more
wiley   +1 more source

A QPTAS for Facility Location on Unit Disk Graphs [PDF]

open access: green
Friggstad, Zachary   +3 more
openalex   +3 more sources

In Situ X‐Ray Tomography and Acoustic Emission Monitoring of Damage Evolution in C/C‐SiC Composites Fabricated by Liquid Silicon Infiltration

open access: yesAdvanced Science, EarlyView.
This study investigates how the internal structure of fiber‐reinforced ceramic composites affects their resistance to damage. By combining 3D X‐ray imaging with acoustic emission monitoring during mechanical testing, it reveals how silicon distribution influences crack formation.
Yang Chen   +7 more
wiley   +1 more source

Improper colouring of unit disk graphs

open access: yes, 2007
Motivated by a satellite communications problem, we consider a generalised colouring problem on unit disk graphs. A colouring is k -improper if no vertex receives the same colour as k +1 of its neighbours. The k -improper chromatic number chi_k (G) is the least number of colours needed in a k -improper colouring of a graph G.
Havet, Frédéric   +2 more
openaire   +1 more source

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

open access: yesAdvanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan   +20 more
wiley   +1 more source

Modeling face routing in unit disk graphs

open access: diamond, 2015
В. П. Гамаюн   +1 more
openalex   +1 more source

Efficient sub-5 approximations for minimum dominating sets in unit disk graphs [PDF]

open access: green, 2014
Guilherme D. da Fonseca   +3 more
openalex   +1 more source

AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

open access: yesAdvanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao   +14 more
wiley   +1 more source

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