Results 141 to 150 of about 124,717 (298)

A DNA Tetrahedron Delivery Asiatic Acid to Reprogram Mitochondrial Metabolism for Promoting Bone Regeneration via STAT3 Phosphorylation

Advanced Science, EarlyView.
A hyaluronic acid methacrylate (HAMA) hydrogel incorporating DNA tetrahedrons loaded with Asiatic acid (TDN@AA) was developed. HM‐TDN@AA promotes angiogenesis of endothelial cells (ECs), inhibits osteoclastogenesis from bone marrow–derived macrophages (BMDMs), and enhances osteogenesis of mesenchymal stem cells (MSCs) via STAT3‐mediated mitochondrial ...
Yiwen Huang, Yiming Zhang, Yisheng Feng, Qixiang Yang, Beiyuan Gao, Haiyang Xu, Cheng Huang, Kaili Lin, Yuanzhi Xu, Peiqi Zhu   +9 more
wiley   +1 more source

An Intelligent Magneto‐Mechanical Platform for Cellular Sensing in 3D Microenvironments

Advanced Science, EarlyView.
This study presents MagMI, a pioneering machine intelligence‐driven magneto‐mechanical sensing platform. It utilizes magneto‐mechanical arrays and machine learning to achieve label‐free, real‐time monitoring and classification of cellular proliferation dynamics within 3D microenvironments.
Yue Quan, Yuxin Wang, Sen Ding, Bingpu Zhou, Yinning Zhou   +4 more
wiley   +1 more source

Structure‐Dependent Resonant Frequency Engineering of Textile Tactile Sensors Toward Rapid and Precise Braille Recognition Surpassing Human Sensation

Advanced Science, EarlyView.
A resonant frequency engineering strategy is proposed to modulate the sensibility of piezoresistive textile‐based tactile sensor. It achieves simultaneous detection of static pressure and dynamic vibrations across an unprecedented bandwidth of 5–600 Hz, surpassing human sensation, therefore enables rapid and precise braille recognition.
Xianhong Zheng, Runrun Zhang, Yu Shi, Zhao Zhang, Guiyang Li, Zhengliang Shang, Xin Liu, Fan Zhao, Sheng Hu, Ran Xu, Shuai Wang, Zhiqi Zhao, Zhi Liu, Lihua Zou, Xu Han, Zongqian Wang, Wei Huang, Gengzhi Sun   +17 more
wiley   +1 more source

Hardware acceleration of number theoretic transform for zk‐SNARK

Engineering Reports, EarlyView., 2023
An FPGA‐based hardware accelerator with a multi‐level pipeline is designed to support the large‐bitwidth and large‐scale NTT tasks in zk‐SNARK. It can be flexibly scaled to different scales of FPGAs and has been equipped in the heterogeneous acceleration system with the help of HLS and OpenCL.
Haixu Zhao, Dong Ding, Feng Wang, Pengcheng Hua, Ning Wang, Qin Wu, Zhilei Chai   +6 more
wiley   +1 more source

High‐Conductivity Electrolytes Screened Using Fragment‐ and Composition‐Aware Deep Learning

Advanced Science, EarlyView.
We present a new deep learning framework that hierarchically links molecular and functional unit attributions to predict electrolyte conductivity. By integrating molecular composition, ratios, and physicochemical descriptors, it achieves accurate, interpretable predictions and large‐scale virtual screening, offering chemically meaningful insights for ...
Xiangwen Wang, Muyang Chen, Gengyi Bao, Yan Lai, Jinghe Cao, Xinhua Liu, Rui Tan   +6 more
wiley   +1 more source

Distributed coloring and the local structure of unit-disk graphs [PDF]

, 2022
Louis Esperet, Sébastien Julliot, Arnaud de Mesmay   +2 more
openalex   +1 more source

Room‐Temperature Magnetic Skyrmions and Intrinsic Anomalous Hall Effect in a Nodal‐Line Kagomé Ferromagnet MnRhP

Advanced Science, EarlyView.
MnRhP has been identified as a novel kagomé magnet that hosts magnetic skyrmions above room temperature and exhibits a large intrinsic anomalous Hall effect. The latter originates from Berry curvature associated with gapped nodal lines, establishing MnRhP as a promising platform for exploring high‐temperature topological phenomena in both real and ...
Kosuke Karube, Ming‐Chun Jiang, Lukas Keller, Jonathan S. White, Yi Ling Chiew, Xiuzhen Yu, Guang Yu Guo, Ryotaro Arita, Yoshinori Tokura, Yasujiro Taguchi   +9 more
wiley   +1 more source

Single‐Cell Morphomechanics of Prostate Cancer‐Associated Fibroblasts Identifies Distinct Features Associated with Patient Outcome

Advanced Science, EarlyView.
Cancer‐associated fibroblasts (CAFs) in prostate tumors exhibit distinct morphomechanical traits vs normal fibroblasts, including greater stiffness and volume, more elongated stress fibres, and larger and more elongated nuclei. These features, quantified through imaging and real‐time deformability cytometry, correlate with patient outcomes and can be ...
Antje Garside, Angela Jacobi, Shivakumar Keerthikumar, Vaibhav Mahajan, Michelle Richards, Birunthi Niranjan, Linda Teng, Nicholas Choo, Johannes Low Jun Wei, Gail P Risbridger, Mitchell G Lawrence, Anna V. Taubenberger   +11 more
wiley   +1 more source

Lactylation Reprogramming in the Bone Infection Microenvironment Identifies PGK1 K361 as a Potential Therapeutic Target for Osteogenic Dysfunction

Advanced Science, EarlyView.
Staphylococcus aureus (S. aureus) infection creates a high‐lactate microenvironment, promoting p300‐mediated lactylation of PGK1 at lysine 361 (K361). Lactylated PGK1 translocates to the mitochondrial outer membrane and interacts with VDAC3. This interaction triggers FtMt downregulation, iron accumulation, and excessive PINK1/Parkin‐mediated mitophagy,
Han‐jun Qin, Si‐ying He, Ting‐hui Xiao, Da‐mao Dai, Xin‐jia Hu, Nan Jiang   +5 more
wiley   +1 more source

Deep Imputation for Skeleton data (DISK) for behavioral science. [PDF]

Nat Methods
Rose F, Michaluk M, Blindauer T, Ignatowska-Jankowska BM, O'Shaughnessy L, Stephens GJ, Pereira TD, Uusisaari MY, Bozek K.   +8 more
europepmc   +1 more source