Results 71 to 80 of about 1,766,233 (264)
Group rings with $FC$-nilpotent unit groups
Let U(RG) be the unit group of the group ring RG. Groups G such that U(RG) is FC-nilpotent are determined, where R is the ring of integers Z or a field K of characteristic ...
openaire +5 more sources
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Namen. Pandemija debelosti pri mladostnikih predstavlja enega večjih izzivov za javno zdravje.
Boričić Katarina +3 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Group algebras with unit group of class $p$
Let V(F_pG) be the group of normalized units of the group algebra F_pG of a finite nonabelian p-group G over the field F_p of p elements. Our goal is to investigate the power structure of V(F_pG), when it has nilpotency class p. As a consequence, we have proved that if G and H are p-groups with cyclic Frattini subgroups and p>2, then V(F_pG) is ...
Balogh, Zsolt, Bovdi, Adalbert
openaire +2 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Group algebras of Kleinian type and groups of units
The algebras of Kleinian type are finite dimensional semisimple rational algebras $A$ such that the group of units of an order in $A$ is commensurable with a direct product of Kleinian groups. We classify the Schur algebras of Kleinian type and the group algebras of Kleinian type.
Del Rio Mateos, Angel +1 more
openaire +4 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Synthesis of Bipyridine Ether-Type Bifunctional Precursors
Bipyridine ethers are commonly occurring structural motifs in supramolecular chemistry. The herein reported efforts aim to extend the synthetic platform of bipyridino-precursors with new bifunctional intermediates and to improve some previously reported ...
Bálint Jávor +8 more
doaj +1 more source

