Results 111 to 120 of about 4,784,645 (352)

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Energy Consumption and Financial Development in NAFTA Countries, 1971–2015

open access: yesApplied Sciences, 2019
To satisfy human needs and desires, it is necessary to produce goods and services that require the use of some production factors, such as labor, capital, and energy, among others.
Mario Gómez, José Carlos Rodríguez
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Re-examining inequality persistence

open access: yesEconomics: Journal Articles, 2020
Although it is not a new phenomenon, in recent years inequality has moved to the top of the political agenda given the concern that will result in political instability and social resentment.
Ghoshray Atanu   +2 more
doaj   +1 more source

Greenberg's conjecture and units in multiple Z_p-extensions [PDF]

open access: yesarXiv, 2000
In this paper we prove Greenberg's pseudo-null conjecture for the field of p-th roots of unity in the case that p exactly divides the class number and the index of the global units in the local units. We also generalize to the case of multiple Z_p-extensions a theorem of Iwasawa on the Kummer extension of the cyclotomic Z_p-extension generated by p ...
arxiv  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Assessing the Fiscal Sustainability of Government Finances in European Countries

open access: yesLithuanian Journal of Statistics, 2013
This paper analyses the fiscal sustainability of government finances in the 27 EU countries and Norway using an empirical, statistical approach and ADF tests for a unit root in the time series of the differences between the GDP growth rate and the long ...
Yuriy Melnykov
doaj   +1 more source

Meromorphy of the rank one unit root L-function revisited [PDF]

open access: yesarXiv, 2013
We demonstrate that Wan's alternate description of Dwork's unit root L-function in the rank one case may be modified to give a proof of meromorphy that is classical, eliminating the need to study sequences of uniform meromorphic functions.
arxiv  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Unit Root Tests in ARMA Models with Data-Dependent Methods for the Selection of the Truncation Lag

open access: yes, 1995
We analyze the choice of the truncation lag in the context of the Said-Dickey test for the presence of a unit root in a general autoregressive moving average model.
Serena Ng, Pierre Perron
semanticscholar   +1 more source

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