Results 111 to 120 of about 879,913 (298)
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Unit roots in macroeconomic time series: theory, implications, and evidence
Nova Economia, 2009 The theme of unit roots in macroeconomic time series has received a great amount of theoretical and applied research in the last two decades. This paper presents some of the main issues regarding unit root tests, explores some of the implications for ...
Gilberto Libânio
doaj
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Testing for seasonal unit roots in Brazilian monetary series
Economia Aplicada, 2002 The objective of this paper is to study the time series properties ofseveral Brazilian monthly monetary series. The test procedures proposed by Beaulieu and Miron (1993) are applied to determine the presence of unit roots at the zero frequency as well ...
Antonio Aguirre
doaj
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Bootstrapping Autoregressive Processes with Possible Unit Roots [PDF]
An important question in applied work is how to bootstrap autoregressive processes involving highly persistent time series of unknown order of integration.
Atsushi Inoue, Lutz Kilian
core
Two-dimensional shapes and lemniscates [PDF]
, 2010 A shape in the plane is an equivalence class of sufficiently smooth Jordan curves, where two curves are equivalent if one can be obtained from the other by a translation and a scaling.
Ebenfelt, P. +2 more
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Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Do real exchange rates have autoregressive unit roots? a test under the alternative of long memory and breaks [PDF]
In this paper, we estimate (by maximum likelihood) the parameters of univariate fractionally integrated real exchange rate time series models, and test for autoregressive unit roots on the alternative of a covariance stationary long-memory process.
Apostolos Serletis, Michael Dueker
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