Results 101 to 110 of about 4,848,832 (374)

On the Construction of Spherical Designs

open access: yesTrends in Computational and Applied Mathematics, 2007
We study special subsets of the unit sphere in Rm, m 2, the socalled spherical designs in the literature. Among other things we introduce a new equivalence for the concept and investigate the construction of designs through rotations of Rm and ...
L.C. Leal Junior, V.A. Menegatto
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Compression on the digital unit sphere

open access: yesElectronic Journal of Differential Equations, 2001
A method for compressing functions on the unit sphere is presented. This method is based on a Ramanujan set of rotations, and generates an equidistributed system of points.
Mohamed Allali
doaj  

Two Perspectives of the 2D Unit Area Quantum Sphere and Their Equivalence [PDF]

open access: yes, 2015
2D Liouville quantum gravity (LQG) is used as a toy model for 4D quantum gravity and is the theory of world-sheet in string theory. Recently there has been growing interest in studying LQG in the realm of probability theory: David et al.
Juhan Aru, Yichao Huang, Xin Sun
semanticscholar   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Hypersurfaces in a Euclidean space with a Killing vector field

open access: yesAIMS Mathematics
An odd-dimensional sphere admits a killing vector field, induced by the transform of the unit normal by the complex structure of the ambiant Euclidean space.
Mohammed Guediri, Sharief Deshmukh
doaj   +1 more source

On Uniform Homeomorphisms of the Unit Spheres of Certain Banach Lattices [PDF]

open access: yesarXiv, 1992
We prove that if X is an infinite dimensional Banach lattice with a weak unit then there exists a probability space (Omega, Sigma,mu) so that the unit sphere S(L_1(Omega, Sigma, mu) is uniformly homeomorphic to the unit sphere S(X) if and only if X does not contain l_{infty}^n's uniformly.
arxiv  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

A complete characterization of Radon planes whose unit spheres are regular polygons

open access: yes, 2018
We study the structure of the unit sphere of polygonal Radon planes from a geometric point of view. In particular, we prove that a $ 2 $-dimensional real polygonal Banach space $ \mathbb{X} $ cannot be a Radon plane if the number of vertices of its unit ...
Mandal, Kalidas   +2 more
core  

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

open access: yesMolecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

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