Results 121 to 130 of about 4,848,832 (374)

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

open access: yesFEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren   +8 more
wiley   +1 more source

On the developable ruled surfaces Kinematically generated in Minkowski 3-Space

open access: yesKuwait Journal of Science, 2014
In this paper, we present a method to be developable of a ruled surface, generated in Minkowski 3-space R corresponding to the dual Lorentzian curves according to E. Study's transference principle and some theorems and examples.
HACI BAYRAM KARADAg١   +2 more
doaj  

Cohomogeneity one actions on unit spheres [PDF]

open access: yesarXiv, 2017
In this paper, we provide a complete classification for all the isometric cohomogeneity one actions on unit spheres. Using this theory, we can very easily classify all the isometric cohomogeneity one actions on the Riemannian symmetric spaces $\mathbb{C}\mathrm{P}^{m-1}$ and $\mathbb{H}\mathrm{P}^{m-1}$.
arxiv  

On the shape of the unit sphere in 𝑄(Δ) [PDF]

open access: yesProceedings of the American Mathematical Society, 1993
We show that the unit sphere in the Banach space of L 1 {L^1} holomorphic quadratic differentials on the disk is weakly uniformly convex with exponent 1 / 2 1/2 at certain points.
openaire   +2 more sources

A real formula for transition probabilities

open access: yesStatistica, 2007
Transition probabilities between states in two dimensional quantum systems are derived as functions of unit vectors in R3 instead of state vectors in C2.
Alessandra Luati
doaj   +1 more source

Extending surjective isometries defined on the unit sphere of $\ell_\infty(Γ)$ [PDF]

open access: yesarXiv, 2017
Let $\Gamma$ be an infinite set equipped with the discrete topology. We prove that the space $\ell_{\infty}(\Gamma),$ of all complex-valued bounded functions on $\Gamma$, satisfies the Mazur-Ulam property, that is, every surjective isometry from the unit sphere of $\ell_{\infty}(\Gamma)$ onto the unit sphere of an arbitrary complex Banach space $X ...
arxiv  

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

open access: yesFEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui   +5 more
wiley   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

open access: yesFEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi   +4 more
wiley   +1 more source

Distinct distances on a sphere [PDF]

open access: yesarXiv, 2004
We study the Erdos distance conjecture on the unit sphere in three dimensions using Fourier analytic methods.
arxiv  

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