Results 71 to 80 of about 4,848,832 (374)
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
FEBS Letters, EarlyView.miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan +10 more
wiley +1 more source
Characterization of Clifford Torus in Three-Spheres
Mathematics, 2020 We characterize spheres and the tori, the product of the two plane circles immersed in the three-dimensional unit sphere, which are associated with the Laplace operator and the Gauss map defined by the elliptic linear Weingarten metric defined on closed ...
Dong-Soo Kim, Young Ho Kim, Jinhua Qian
doaj +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
A note on five dimensional kissing arrangements [PDF]
arXiv, 2023 The kissing number $\tau(d)$ is the maximum number of pairwise non-overlapping unit spheres each touching a central unit sphere in the $d$-dimensional Euclidean space. In this note we report on how we discovered a new, previously unknown arrangement of $40$ unit spheres in dimension $5$. Our arrangement saturates the best known lower bound on $\tau(5)$,
arxiv
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
Strict positive definiteness on spheres via disk polynomials
International Journal of Mathematics and Mathematical Sciences, 2002 We characterize complex strictly positive definite functions on spheres in two cases, the unit sphere of ℂq, q≥3, and the unit sphere of the complex ℓ2. The results depend upon the Fourier-like expansion of the functions in terms of disk polynomials and,
V. A. Menegatto, A. P. Peron
doaj +1 more source
Which geodesic flows are left-handed ?
, 2017 We prove that the geodesic flow on the unit tangent bundle to a hyperbolic 2-orbifold is left-handed if and only if the orbifold is a sphere with three conic points.
Dehornoy, Pierre
core +2 more sources
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
A novel formulation of point vortex dynamics on the sphere: geometrical and numerical aspects
, 2013 In this paper, we present a novel Lagrangian formulation of the equations of motion for point vortices on the unit 2-sphere. We show first that no linear Lagrangian formulation exists directly on the 2-sphere but that a Lagrangian may be constructed by ...
Leok, Melvin, Vankerschaver, Joris
core +1 more source