Results 241 to 250 of about 3,692,993 (315)

De Novo Design of Membrane‐Targeting Antimicrobial Peptides Against Gram‐Negative Bacteria Using a Generative Artificial Intelligence Framework

Advanced Science, EarlyView.
Antimicrobial resistance caused by Gram‐negative bacteria remains difficult to overcome due to the protective outer membrane. To address this challenge, a multi‐condition constrained generative AI framework, GenMTAMP is proposed for de novo membrane‐targeting antimicrobial peptide design by integrating physicochemical and spatial structure descriptors.
Jingxiao Yu, Da‐Wen Sun, QingYi Wei, Yibing Zhang, Jidong Tang, Hongbin Pu   +5 more
wiley   +1 more source

Botulinum Toxin and Redress in the United Kingdom, Findings From a Cross-Sectional Survey. [PDF]

J Cosmet Dermatol
Smith L, López-Gil JF, Rahmati M, Gawronska J, Ravindran R.   +4 more
europepmc   +1 more source

Epidermal METTL1‐Mediated m7G Modification Drives Psoriatic Inflammation by Stabilizing Bdkrb1 and Orchestrating Neutrophil Recruitment

Advanced Science, EarlyView.
This study unveils an unrecognized pro‐inflammatory epitranscriptomic checkpoint in psoriasis. By installing m7G modifications on the 5′ UTR of Bdkrb1 mRNA, METTL1 enhances receptor stability to orchestrate keratinocyte‐driven neutrophil recruitment via p38 MAPK signaling.
Chang Zhang, Jiayi Lu, Sihao Yan, Yirui Wang, Zhuo Li, Weiwei Chen, Yang Han, Ziyan Zhang, Yafen Yu, Qi Zhen, Liangdan Sun   +10 more
wiley   +1 more source

A Thematic Analysis Exploring Bowel Cancer Screening Promotional Visuals in the United Kingdom and India. [PDF]

Health Lit Res Pract
Yfantidou I, Palace M, von Wagner C, Stoffel S, Santos Barea C, Smith L, May B, Srivastava M, Samuel J.   +8 more
europepmc   +1 more source

Magnetotransport Signatures of Spin–Orbit Coupling in High‐Temperature Cuprate Superconductors

Advanced Science, EarlyView.
Large angle‐dependent magnetoresistance and planar Hall effects emerge at the superconducting transition of YBa2Cu3O7−x$\mathrm{YBa_2Cu_3O_{7-x}}$ thin films. These anomalous transport signatures, absent in the normal state, point to spin‐polarized quasiparticle dynamics enabled by an unexpected spin–orbit coupling landscape in cuprate superconductors,
Aleix Barrera, Huidong Li, Thomas Gunkel, Jordi Alcalá, Silvia Damerio, Can Onur Avci, Anna Palau   +6 more
wiley   +1 more source

A protocol for an emergency front-of-neck airway registry in the United Kingdom. [PDF]

BJA Open
Ghosh P, McNarry AF, Cook T, Jimbu N, Cortés L, El-Boghdadly K, Ahmad I, Taylor C, Moppett IK.   +8 more
europepmc   +1 more source

An exciting Approach to Theoretical Spectroscopy

Advanced Science, EarlyView.
ABSTRACT Theoretical spectroscopy, and more generally, electronic‐structure theory, are powerful concepts for describing the complex many‐body interactions in materials. They cover methods from ground‐state properties to lattice excitations and light‐matter interaction, including time‐resolved variants.
Martí Raya‐Moreno, Alexander Buccheri, Noah Alexy Dasch, Nasrin Farahani, Ignacio Gonzalez Oliva, Andris Gulans, Seokhyun Hong, Manoar Hossain, Hannah Kleine, Martin Kuban, Sven Lubeck, Benedikt Maurer, Pasquale Pavone, Fabian Peschel, Daria Popova‐Gorelova, Lu Qiao, Elias Richter, Santiago Rigamonti, Ronaldo Rodrigues Pela, Maximilian Schebek, Kshitij Sinha, Daniel T. Speckhard, Jan Stutz, Sebastian Tillack, Dmitry Tumakov, Jānis Užulis, Mara Voiculescu, Cecilia Vona, Mao Yang, Claudia Draxl   +29 more
wiley   +1 more source

Quality of life of X-linked agammaglobulinemia patients in the United Kingdom. [PDF]

J Hum Immun
Shillitoe B, Bourne H, Stroud C, Flood T, Buckland M, Ip W, Worth A, Hackett S, Herwadkar A, Coulter T, Jolles S, Garcez T, Moya E, Faust SN, Pearce MS, Gennery AR.   +15 more
europepmc   +1 more source