Results 321 to 330 of about 7,384,422 (405)

TVB C++: A Fast and Flexible Back‐End for The Virtual Brain

open access: yesAdvanced Science, EarlyView.
TVB C++ is a streamlined and fast C++ Back‐End for The Virtual Brain (TVB), designed to make it as flexible as TVB, and FAST. Another pillar is to be fully compatible with TVB so easy bindings can be created from Python. Users can easily configure TVB C++ to execute the same code but with enhanced performance and parallelism.
Ignacio Martín   +7 more
wiley   +1 more source

Exploring Functionally Enhanced BLP‐Trained Macrophage Subpopulations in S. Aureus Infection: Underlying Mechanisms and Therapeutic Significance

open access: yesAdvanced Science, EarlyView.
BLP‐trained macrophages show augmented resistance to infection, but their mechanisms remain unclear. scRNA‐seq identified 13 BMDM subsets, with two novel anti‐inflammatory/antibacterial subpopulations (C5/C7) emerging post‐BLP training. BLP training activates NRF2, attenuates oxidative stress/ferroptosis, and boosts glycolysis/OXPHOS. Adoptive transfer
Yantong Wan   +13 more
wiley   +1 more source

Intersectionality and Long Covid: Understanding the Lived Experiences of Ethnic Minority Groups in the United Kingdom. [PDF]

open access: yesHealth Expect
Lotankar Y   +8 more
europepmc   +1 more source

Larger rock extraction sites could improve the efficiency of enhanced rock weathering in the United Kingdom

open access: gold
Mohammad Madankan   +7 more
openalex   +1 more source

Lnc‐HZ05 Suppresses Trophoblast Cell Migrasome Formation by Disrupting TGFβ2 Pathway in Unexplained Recurrent Miscarriage

open access: yesAdvanced Science, EarlyView.
TGFβ2 signaling‐mediated migration/invasion and migrasome formation are suppressed in recurrent miscarriage (RM) versus healthy control villous tissues and are negatively associated with unexplained RM. In mechanism, TGFβ2 promotes trophoblast cell migration/invasion and migrasome formation, all of which are suppressed by lnc‐HZ05. In details, lnc‐HZ05
Weina Chen   +14 more
wiley   +1 more source

Perceived Digital Well-Being Scale in the United States and United Kingdom: Psychometric Validation Study.

open access: yesJMIR Ment Health
Vera Cruz G   +8 more
europepmc   +1 more source

Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids

open access: yesAdvanced Science, EarlyView.
Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang   +6 more
wiley   +1 more source

National Variation in the Use of Multiple Arterial Grafting in Isolated Coronary Artery Bypass Grafting in the United Kingdom. [PDF]

open access: yesEur J Cardiothorac Surg
Chan J   +6 more
europepmc   +1 more source

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