Results 111 to 120 of about 10,498,745 (302)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

A New Name (Pneumocystis jiroveci) for Pneumocystis from Humans (Response to Hughes)

open access: yesEmerging Infectious Diseases, 2003
James R. Stringer   +3 more
doaj   +1 more source

The United States Marines

open access: yes, 1945
Front: Text describes American advancement and control of Korean and Japanese cities after Japan's formal surrender on 1 Sept., United States time Map shows Japan and Korea. Photographs: Gen.
[United States.] Army Service Forces. Army Information Branch.
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Food Safety for First Responders

open access: yesEmerging Infectious Diseases, 2005
Mary K. Afton   +3 more
doaj   +1 more source

Farmers' bulletin (United States. Dept. of Agriculture)

open access: yes, 1922
Describes several varieties of club wheats and where they grow in the United ...
Clark, J. Allen (Jacob Allen), b. 1888   +2 more
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Something Money Can't Buy - United States Army Tradition!

open access: yes, 1943
Front: Text describes action on various war fronts: Italy, Yugoslavia, Air offensive, Southwest Pacific, Russia. Maps show military activities in Eurasia and New Guinea near Salamaua with boxed text highlighting action.
[United States.] Army Orientation Course.
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

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