Results 151 to 160 of about 787,943 (334)

The H2 Blockers' Rx-to OTC Switch: For Whom Will It Spell Relief? [PDF]

open access: yes, 2012
Tylenol. Advil. Monistat 7. Imodium AD. These are some of the most commonly used, widely available, and successful drugs in the United States. All of them began as drugs only available by a prescription. All of them made a successful prescription-only to
Kisloff, Michelle A.
core  

Unleashing the Power of Machine Learning in Nanomedicine Formulation Development

open access: yesAdvanced Functional Materials, EarlyView.
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore   +7 more
wiley   +1 more source

Is the Food and Drug Administration Safe and Effective? [PDF]

open access: yes
In the United States, drug safety and efficacy are primarily regulated by the Food and Drug Administration (FDA) and the legal system, which gives manufacturers large incentives to produce safe drugs and provide proper warnings for side effects, since ...
Eric Sun, Tomas J. Philipson
core  

cGMP Recombinant FIX for IV and Oral Hemophilia B Therapy [PDF]

open access: yes, 2005
Three specific aims are proposed: Specific Aim # 1. Process engineer and scale-up the recovery and purification of transgenic recombinant human Factor IX.
Dernell, William, KEY PERSON   +9 more
core   +1 more source

Light‐Responsive Enzyme‐Loaded Nanoparticles for Tunable Adhesion and Mechanical Wound Contraction

open access: yesAdvanced Functional Materials, EarlyView.
This study presents a photoactivatable enzyme‐loaded mesoporous nanoparticle system (MPDA_PaTy) that enables light‐triggered tunable tissue adhesion and facilitates mechanical wound contraction. Controlled enzymatic crosslinking at tissue or hydrogel interfaces allows on‐demand adhesion.
Junghyeon Ko   +10 more
wiley   +1 more source

Bio‐Friendly Artificial Muscles Based on Carbon Nanotube Yarns and Eutectogel Derivatives

open access: yesAdvanced Functional Materials, EarlyView.
Solid‐state artificial muscles based on coiled commercial carbon nanotube yarns coated with eutectogel derivatives exhibit unipolar actuation through selective ion intercalation. Combining polyanionic and polycationic gels enables enhanced contractile stroke and high energy density.
Gabriela Ananieva   +6 more
wiley   +1 more source

AI-powered topic modeling: comparing LDA and BERTopic in analyzing opioid-related cardiovascular risks in women

open access: yesExperimental Biology and Medicine
Topic modeling is a crucial technique in natural language processing (NLP), enabling the extraction of latent themes from large text corpora. Traditional topic modeling, such as Latent Dirichlet Allocation (LDA), faces limitations in capturing the ...
Li Ma   +9 more
doaj   +1 more source

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