Unleashing the Power of Machine Learning in Nanomedicine Formulation Development
Advanced Functional Materials, EarlyView.A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore +7 more
wiley +1 more source
Drug-induced torsades de pointes: Disproportionality analysis of the United States Food and Drug Administration adverse event reporting system. [PDF]
Front Cardiovasc Med, 2022 Wu Z, Zhou P, He N, Zhai S.
europepmc +1 more source
Navigating commercial approval of therapeutics: The evolution of the United States Food and Drug Administrations [PDF]
, 2015 Dillon K. Jarrell +4 more
openalex +1 more source
Light‐Responsive Enzyme‐Loaded Nanoparticles for Tunable Adhesion and Mechanical Wound Contraction
Advanced Functional Materials, EarlyView.This study presents a photoactivatable enzyme‐loaded mesoporous nanoparticle system (MPDA_PaTy) that enables light‐triggered tunable tissue adhesion and facilitates mechanical wound contraction. Controlled enzymatic crosslinking at tissue or hydrogel interfaces allows on‐demand adhesion.
Junghyeon Ko +10 more
wiley +1 more source
Doxycycline use and adverse pregnancy or neonatal outcomes: A descriptive study using the United States Food and Drug Administration Adverse Event Reporting System database. [PDF]
Health Sci Rep, 2022 Kaundinnyayana S, Kamath A.
europepmc +1 more source
Ice Lithography: Recent Progress Opens a New Frontier of Opportunities
Advanced Functional Materials, EarlyView.This review focuses on recent advancements in ice lithography, including breakthroughs in compatible precursors and substrates, processes and applications, hardware, and digital methods. Moreover, it offers a roadmap to uncover innovation opportunities for ice lithography in fields such as biological, nanoengineering and microsystems, biophysics and ...
Bingdong Chang +9 more
wiley +1 more source
Comparison of Good Clinical Practice Inspection Processes for Marketing Applications Between the United States Food and Drug Administration and the European Medicines Agency. [PDF]
Ther Innov Regul Sci, 2023 Ayalew K +11 more
europepmc +1 more source
After Heparin: Protecting Consumers From the Risks of Substandard and Counterfeit Drugs [PDF]
, 2011 Based on case studies, examines globalization and quality management trends in pharmaceutical manufacturing, barriers to Federal Drug Administration oversight, and the security of pharmaceutical distribution.
core
pH‐Tunable Material Properties of Glycine‐Rich Condensates from Tick Bioadhesive
Advanced Functional Materials, EarlyView.This work studies the influence of pH on the phase separation behavior of a disordered glycine‐rich protein found in tick bioadhesive. The results show profound impact on the propensity of coacervation, condensate microstructure and viscosity, amphiphilicity of the peptides, and effective encapsulation of therapeutic molecules.
Manali Nandy +5 more
wiley +1 more source
Dietary Exposure to United States Food and Drug Administration-Approved Synthetic Food Colors in Children, Pregnant Women, and Women of Childbearing Age Living in the United States. [PDF]
Int J Environ Res Public Health, 2022 Bradman A +7 more
europepmc +1 more source