Progestin drugs are loaded into a mesoporous silicon dioxide host by melt‐infiltration. Drugs that decompose at or close to their melting point can be loaded by the addition of cholesterol, which acts as a melting point suppressor. High mass loading of the drug is achieved, and dissolution of the composite is controlled by the nanoscale properties of ...
Geoffrey Hollett+13 more
wiley +1 more source
Evaluation of the EVO/EVO+ Sphere and Toric Visian ICL: Six Month Results from the United States Food and Drug Administration Clinical Trial. [PDF]
Packer M.
europepmc +1 more source
DEVELOPMENT OF PRODUCTS TO PROMOTE BOWEL CLEANSING FOR COLONOSCOPY—DRAFT GUIDANCE FROM THE UNITED STATES FOOD AND DRUG ADMINISTRATION [PDF]
Anil K. Nayyar+2 more
openalex +1 more source
Engineering the Future of Restorative Clinical Peripheral Nerve Surgery
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell+5 more
wiley +1 more source
Assessment of pancreatitis associated with tocilizumab use using the United States Food and Drug Administration Adverse Event Reporting System database. [PDF]
Kamath A, Acharya SD, Rao RR, Ullal SD.
europepmc +1 more source
Real-world study of antifibrotic drugs-related adverse events based on the United States Food and Drug Administration Adverse Event Reporting System and VigiAccess databases [PDF]
M. He+4 more
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Thermoresponsive BrushGel Microcarriers for Efficient Cell Expansion and Enzyme‐Reduced Harvesting
Askari et al, report on temperature‐responsive microcarriers to minimize enzyme use and cost in dynamic cultures. Abstract Scaling up cell therapy requires efficient expansion of high‐quality cells. Microcarrier(MC)‐based systems offer high surface‐to‐volume ratios and reduce culture media usage.
Esfandyar Askari+9 more
wiley +1 more source
Adverse events related to total ankle replacement devices: an analysis of reports to the United States Food and Drug Administration. [PDF]
Mahmoud K+3 more
europepmc +1 more source
A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang+9 more
wiley +1 more source