Results 81 to 90 of about 756,003 (352)
Paired metagenomic and chemical evaluation of aflatoxin-contaminated dog kibble
Frontiers in Veterinary ScienceIntroductionIdentification of chemical toxins from complex or highly processed foods can present ‘needle in the haystack’ challenges for chemists. Metagenomic data can be used to guide chemical toxicity evaluations by providing DNA-based description of ...
Andrea Ottesen +8 more
doaj +1 more source
Frontiers in Public Health, 2017 Recently, we have identified a link between four listeriosis incidents/outbreaks to a variant of Listeria monocytogenes (Lm) serotype 4b strains, 4bV.
Laurel S. Burall +3 more
doaj +1 more source
Targeting cancer with antibody-drug conjugates: Promises and challenges
mAbs, 2021 Antibody-drug conjugates (ADCs) are a rapidly expanding class of biotherapeutics that utilize antibodies to selectively deliver cytotoxic drugs to the tumor site. As of May 2021, the U.S.
Alexis Q. Dean +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Global Environmental Law: Food Safety & China [PDF]
, 2013 This article makes the case for food security law and policy as a component of global environmental law in recognition of the global economy, trade liberalization, and concerns for food safety and environmental harm. It further describes rule of law as a
Czarnezki, Jason J.
core +1 more source
Targeting Angiogenesis in Cancer Therapy [PDF]
, 2011 Angiogenesis is an essential process in tumor growth. The concept of angiogenesis, when proposed by Folksman in 1971, had a great impact on cancer research and therapy, as the survival and proliferation of cancer depend on angiogenesis, which could be a ...
Ichihara, Eiki +2 more
core +1 more source
A network of regulatory innovations to improve FDA quality assessments of human drug applications
International Journal of Pharmaceutics: XA network of regulatory innovations brings a holistic approach to improving the submission, assessment, and lifecycle management of pharmaceutical quality information in the U.S. This dedicated effort in the FDA’s Center for Drug Evaluation and Research (
Russie Tran +10 more
doaj +1 more source
Sample Size Determination for Food Sampling
Journal of Food Protection, 2023 Industry and public health agencies sample and test food products for various purposes related to food safety and quality. Methods of sample selection and sample size determination are important in designing an optimal sampling plan.
Shizhen S. Wang +3 more
doaj +1 more source
The United States Food and Drugs Administration Approves a Generic Enoxaparin
Clinical and Applied Thrombosis/Hemostasis, 2010 The Food and Drug Administration (FDA) approved on July 23, 2010, the abbreviated new drug application (ANDA) by Sandoz Inc for a generic enoxaparin (Lovenox) as the FDA is satisfied with the active ingredient ‘‘sameness’’ and the interchangeability of Lovenox with this generic version.
openaire +3 more sources
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source