Results 151 to 160 of about 2,073,663 (243)

An Optimization Method for an Active Multi-Unit Prosthetic Socket with Dynamic Adaptability in Multi-Task Scenarios. [PDF]

Biomimetics (Basel)
Hu Y, Jiang L, Zou C, Yang B, Han T, Cheng M.   +5 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Expansive spatial pattern of Aβ deposition in patients with cerebral amyloid angiopathy: A three-dimensional surface-to-depth analysis. [PDF]

Sci Adv
Hayashi H, Saito R, Miyashita A, Ikeuchi T, Tada M, Akazawa K, Onodera O, Tainaka K, Kakita A.   +8 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

A prefrontal cortex map based on single-neuron activity. [PDF]

Nat Neurosci
Le Merre P, Heining K, Slashcheva M, Jung F, Moysiadou E, Guyon N, Yahya R, Park H, Wernstal F, Carlén M.   +9 more
europepmc   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Do mandibular functional units exhibit inherent asymmetry in adults with a normal degree of chin deviation? A cone-beam computed tomography study. [PDF]

Sci Rep
Daraqel B, Mheissen S, Cao L, Yang D, Huang Y, Zhang T, Zheng L.   +6 more
europepmc   +1 more source

Mitochondria unite [PDF]

Nature Reviews Molecular Cell Biology, 2018
openaire   +2 more sources

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

The amidation of poly(styrene-<i>alt</i>-maleic anhydride) <i>via N</i>,<i>N</i>-dimethylformamide decomposition.

Polym Chem
Smith MP, Ball LE, Wessels I, Klumperman B.   +3 more
europepmc   +1 more source