Results 121 to 130 of about 2,258,944 (274)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Cooking the volumes

open access: yes, 2012
Cooking possesses a system of units of measurement, that includes measures of volumes based on pre-metric units. This paper discusses the cooking measures and compares their features with those of the ancient Roman measures of capacity.Comment: Roman ...
Sparavigna, Amelia Carolina
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

A Review of Gait Analysis Using Gyroscopes and Inertial Measurement Units

open access: yesSensors
Wearable sensors are used in gait analysis to obtain spatiotemporal parameters, with gait events serving as critical markers for foot and lower limb movement.
Sheng Lin   +6 more
doaj   +1 more source

Miniature interferometer terminals for earth surveying [PDF]

open access: yes
A system of miniature radio interferometer terminals was proposed for the measurement of vector baselines with uncertainties ranging from the millimeter to the centimeter level for baseline lengths ranging, respectively, from a few to a few hundred ...
Counselman, C. C., III, Shapiro, I. I.
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Smith e Keynes sobre as unidades de salário [Smith and Keynes on wage units] [PDF]

open access: yes
The paper analyses Adam Smith's labour commanded value theory and proceeds with a comparison between this theory and Keynes' wage units approach, demonstrating that both authors were mainly concerned with a nominal anchor to the measure of value.
Adriana Amado
core  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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